Matches in SemOpenAlex for { <https://semopenalex.org/work/W2400246684> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2400246684 abstract "Objective: Coronary artery was ligated to study the characteristics of myocardial ischemia in rats. Methods: The left anterior descending artery was ligated to establish the rat model of acute myocardial ischemia. All animals were divided into normal control group, sham operation group and model group. 1, 2 and 4 weeks after modeling, ECG (II lead) was recorded, the weight of whole heart and left ventricle were recorded and organ indexes were calculated; myocardial infarct size was determined by TTC; CK, CK-MB, LDH, AST contents of serum were detected; cardiac function was determined by left ventricular intubation via carotid artery and left ventricular was taken to perform pathological observation. Results: 1 week after modeling, compared with the sham operation group, the ECG and heart function index of rats model had significant change, but the myocardial enzymes did not change significantly; 4 weeks after modeling, the ECG and cardiac function of animal models had a recovery trend, but the myocardial enzymes, including CK, CK-MB, LDH, AST, were significantly increased; 1 week after modeling, the left ventricular indexes of model rats were increased; the infarct size was about 30%, myocardial cell necrosis and granulation tissue hyperplasia could be observed in infarction area; with the modeling time extended, from 2 to 4 weeks, the left ventricular and heart indexes of model group were significantly increased; the infarct size was relatively constant, left ventricular became thickly, and fibrous or granulation tissue was significantly proliferated in infarction area under microscope. Conclusion: The indexes of myocardial ischemia induced by coronary artery ligation in rats are different at different time points. The results suggest that the time point should be selected to observe the anti-myocardial ischemia effect of the subjects from different aspects." @default.
- W2400246684 created "2016-06-24" @default.
- W2400246684 creator A5008405013 @default.
- W2400246684 creator A5016467420 @default.
- W2400246684 creator A5019045535 @default.
- W2400246684 creator A5023186149 @default.
- W2400246684 creator A5034711601 @default.
- W2400246684 creator A5044544424 @default.
- W2400246684 creator A5059431543 @default.
- W2400246684 creator A5063089557 @default.
- W2400246684 creator A5080815296 @default.
- W2400246684 creator A5083792116 @default.
- W2400246684 date "2016-01-01" @default.
- W2400246684 modified "2023-09-27" @default.
- W2400246684 title "A Study of Myocardial Ischemia Model Induced by Left Coronary Artery Ligation in Rats" @default.
- W2400246684 cites W1999560837 @default.
- W2400246684 cites W2110766488 @default.
- W2400246684 cites W2123810756 @default.
- W2400246684 cites W2132758299 @default.
- W2400246684 cites W2376840169 @default.
- W2400246684 doi "https://doi.org/10.4236/wjcd.2016.65014" @default.
- W2400246684 hasPublicationYear "2016" @default.
- W2400246684 type Work @default.
- W2400246684 sameAs 2400246684 @default.
- W2400246684 citedByCount "4" @default.
- W2400246684 countsByYear W24002466842017 @default.
- W2400246684 countsByYear W24002466842019 @default.
- W2400246684 countsByYear W24002466842020 @default.
- W2400246684 crossrefType "journal-article" @default.
- W2400246684 hasAuthorship W2400246684A5008405013 @default.
- W2400246684 hasAuthorship W2400246684A5016467420 @default.
- W2400246684 hasAuthorship W2400246684A5019045535 @default.
- W2400246684 hasAuthorship W2400246684A5023186149 @default.
- W2400246684 hasAuthorship W2400246684A5034711601 @default.
- W2400246684 hasAuthorship W2400246684A5044544424 @default.
- W2400246684 hasAuthorship W2400246684A5059431543 @default.
- W2400246684 hasAuthorship W2400246684A5063089557 @default.
- W2400246684 hasAuthorship W2400246684A5080815296 @default.
- W2400246684 hasAuthorship W2400246684A5083792116 @default.
- W2400246684 hasBestOaLocation W24002466841 @default.
- W2400246684 hasConcept C111566952 @default.
- W2400246684 hasConcept C126322002 @default.
- W2400246684 hasConcept C164705383 @default.
- W2400246684 hasConcept C179437574 @default.
- W2400246684 hasConcept C2776820930 @default.
- W2400246684 hasConcept C2777798775 @default.
- W2400246684 hasConcept C2778198053 @default.
- W2400246684 hasConcept C2778921608 @default.
- W2400246684 hasConcept C2780231137 @default.
- W2400246684 hasConcept C500558357 @default.
- W2400246684 hasConcept C541997718 @default.
- W2400246684 hasConcept C71924100 @default.
- W2400246684 hasConceptScore W2400246684C111566952 @default.
- W2400246684 hasConceptScore W2400246684C126322002 @default.
- W2400246684 hasConceptScore W2400246684C164705383 @default.
- W2400246684 hasConceptScore W2400246684C179437574 @default.
- W2400246684 hasConceptScore W2400246684C2776820930 @default.
- W2400246684 hasConceptScore W2400246684C2777798775 @default.
- W2400246684 hasConceptScore W2400246684C2778198053 @default.
- W2400246684 hasConceptScore W2400246684C2778921608 @default.
- W2400246684 hasConceptScore W2400246684C2780231137 @default.
- W2400246684 hasConceptScore W2400246684C500558357 @default.
- W2400246684 hasConceptScore W2400246684C541997718 @default.
- W2400246684 hasConceptScore W2400246684C71924100 @default.
- W2400246684 hasLocation W24002466841 @default.
- W2400246684 hasOpenAccess W2400246684 @default.
- W2400246684 hasPrimaryLocation W24002466841 @default.
- W2400246684 hasRelatedWork W2020842271 @default.
- W2400246684 hasRelatedWork W2036968400 @default.
- W2400246684 hasRelatedWork W2108233047 @default.
- W2400246684 hasRelatedWork W2139533617 @default.
- W2400246684 hasRelatedWork W2152175126 @default.
- W2400246684 hasRelatedWork W2350969490 @default.
- W2400246684 hasRelatedWork W2354754655 @default.
- W2400246684 hasRelatedWork W2355333831 @default.
- W2400246684 hasRelatedWork W2355691330 @default.
- W2400246684 hasRelatedWork W2358073086 @default.
- W2400246684 hasRelatedWork W2359362412 @default.
- W2400246684 hasRelatedWork W2360690253 @default.
- W2400246684 hasRelatedWork W2361226809 @default.
- W2400246684 hasRelatedWork W2363749720 @default.
- W2400246684 hasRelatedWork W2374921746 @default.
- W2400246684 hasRelatedWork W2377572766 @default.
- W2400246684 hasRelatedWork W2379322904 @default.
- W2400246684 hasRelatedWork W2386396894 @default.
- W2400246684 hasRelatedWork W2391372354 @default.
- W2400246684 hasRelatedWork W3150846458 @default.
- W2400246684 isParatext "false" @default.
- W2400246684 isRetracted "false" @default.
- W2400246684 magId "2400246684" @default.
- W2400246684 workType "article" @default.