Matches in SemOpenAlex for { <https://semopenalex.org/work/W2400396555> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2400396555 endingPage "20" @default.
- W2400396555 startingPage "513" @default.
- W2400396555 abstract "Cholecystokinin 7 (CCK 7), a synthetic analogue of cholecystokinin/pancreozymin (CCK 33), increased in a dose-dependent manner the tone of the guinea-pig ileal, gastric and gall bladder smooth muscle preparations. In all these preparations CCK 7 was more potent than CCK 8 and CCK 33 and all three cholecystokinins were more potent than acetylcholine (ACH). Atropine and tetrodotoxin (TTX) did not influence the CCK 7 action in fundus and gall bladder muscle strips but reduced non-competitively its effect in ileal muscle strips. Neither GE 410 nor dbcGMP affected the ACH and histamine (His) response of the muscle strips but both antagonists shifted the dose-response curve of CCK 7 to the right, GE 410 (cholecystokinin antagonist) being a much more potent antagonist of CCK 7 as compared to dbcGMP. In all muscle strips a competitive action on the CCK 7 responses was found for GE 410. In gastric muscle strips a competitive influence on the CCK 7 responses was found for dbcGMP at low concentration (1 x 10(-5)M) and a non-competitive influence at high concentration (5 x 10(-4)M). The results suggest that the contractile effects of CCK 7 in the isolated ileal smooth muscle are realized by cholinergic and direct myogenic mechanisms, whereas in the isolated gall bladder and gastric smooth muscles, by a direct myogenic mechanism only." @default.
- W2400396555 created "2016-06-24" @default.
- W2400396555 creator A5015724313 @default.
- W2400396555 creator A5023784884 @default.
- W2400396555 creator A5042225124 @default.
- W2400396555 creator A5060649972 @default.
- W2400396555 creator A5079976354 @default.
- W2400396555 date "1988-08-01" @default.
- W2400396555 modified "2023-09-27" @default.
- W2400396555 title "Responses of guinea-pig gastric, ileal and gall bladder smooth muscle to desamino-cholecystokinin-octapeptide (CCK 7)." @default.
- W2400396555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2852288" @default.
- W2400396555 hasPublicationYear "1988" @default.
- W2400396555 type Work @default.
- W2400396555 sameAs 2400396555 @default.
- W2400396555 citedByCount "1" @default.
- W2400396555 crossrefType "journal-article" @default.
- W2400396555 hasAuthorship W2400396555A5015724313 @default.
- W2400396555 hasAuthorship W2400396555A5023784884 @default.
- W2400396555 hasAuthorship W2400396555A5042225124 @default.
- W2400396555 hasAuthorship W2400396555A5060649972 @default.
- W2400396555 hasAuthorship W2400396555A5079976354 @default.
- W2400396555 hasConcept C1122143 @default.
- W2400396555 hasConcept C126322002 @default.
- W2400396555 hasConcept C134018914 @default.
- W2400396555 hasConcept C170493617 @default.
- W2400396555 hasConcept C185592680 @default.
- W2400396555 hasConcept C22885893 @default.
- W2400396555 hasConcept C2775859210 @default.
- W2400396555 hasConcept C2775910092 @default.
- W2400396555 hasConcept C2776050358 @default.
- W2400396555 hasConcept C2776741303 @default.
- W2400396555 hasConcept C2776885963 @default.
- W2400396555 hasConcept C2777226302 @default.
- W2400396555 hasConcept C2777593968 @default.
- W2400396555 hasConcept C2778815084 @default.
- W2400396555 hasConcept C71924100 @default.
- W2400396555 hasConcept C86803240 @default.
- W2400396555 hasConceptScore W2400396555C1122143 @default.
- W2400396555 hasConceptScore W2400396555C126322002 @default.
- W2400396555 hasConceptScore W2400396555C134018914 @default.
- W2400396555 hasConceptScore W2400396555C170493617 @default.
- W2400396555 hasConceptScore W2400396555C185592680 @default.
- W2400396555 hasConceptScore W2400396555C22885893 @default.
- W2400396555 hasConceptScore W2400396555C2775859210 @default.
- W2400396555 hasConceptScore W2400396555C2775910092 @default.
- W2400396555 hasConceptScore W2400396555C2776050358 @default.
- W2400396555 hasConceptScore W2400396555C2776741303 @default.
- W2400396555 hasConceptScore W2400396555C2776885963 @default.
- W2400396555 hasConceptScore W2400396555C2777226302 @default.
- W2400396555 hasConceptScore W2400396555C2777593968 @default.
- W2400396555 hasConceptScore W2400396555C2778815084 @default.
- W2400396555 hasConceptScore W2400396555C71924100 @default.
- W2400396555 hasConceptScore W2400396555C86803240 @default.
- W2400396555 hasIssue "8" @default.
- W2400396555 hasLocation W24003965551 @default.
- W2400396555 hasOpenAccess W2400396555 @default.
- W2400396555 hasPrimaryLocation W24003965551 @default.
- W2400396555 hasRelatedWork W1983972748 @default.
- W2400396555 hasRelatedWork W1986331265 @default.
- W2400396555 hasRelatedWork W1994001975 @default.
- W2400396555 hasRelatedWork W2014154327 @default.
- W2400396555 hasRelatedWork W2016535499 @default.
- W2400396555 hasRelatedWork W2020769380 @default.
- W2400396555 hasRelatedWork W2047505079 @default.
- W2400396555 hasRelatedWork W2051704966 @default.
- W2400396555 hasRelatedWork W2052414784 @default.
- W2400396555 hasRelatedWork W2085361427 @default.
- W2400396555 hasVolume "10" @default.
- W2400396555 isParatext "false" @default.
- W2400396555 isRetracted "false" @default.
- W2400396555 magId "2400396555" @default.
- W2400396555 workType "article" @default.