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- W2400427092 abstract "A specific rabbit anti-human cathepsin E serum detected this aspartic proteinase in Langerhans cells of the skin, in interdigitating reticulum cells of lymph nodes and spleen and in histiocytosis X cells, but not in macrophages. Immunoblotting of tissue extracts confirmed the presence of cathepsin E in skin and lymph nodes. Electron immunocytochemistry with the protein A gold technique localized cathepsin E in the endoplasmic reticulum and in endosomal vesicles of both interdigitating and Langerhans cells, likely involving Birbeck bodies. A role of endosomal cathepsin E in antigen processing is suggested." @default.
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- W2400427092 date "1993-01-01" @default.
- W2400427092 modified "2023-09-26" @default.
- W2400427092 title "Cathepsin E in antigen-presenting Langerhans and interdigitating reticulum cells. Its possible role in antigen processing." @default.
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