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- W2400686513 abstract "We have previously reported the isolation and characterization of peptides binding to nanoparticles from phage display peptide libraries. One of the peptides (PEP9) was selected and mutant peptide-displaying phages were produced by alanine scanning mutagenesis. The mutant phages were subjected to binding analysis to nanoparticles. When the proline at residue 4 was substituted by alanine, the binding activity was reduced to of that of wild type PEP9. Substitution of valine at residue 2, serine at residue 3, and isoleucine at residue 5 also decreased the binding to . Based on these observations, we concluded that the three dimensional structure generated by residues 2-5 was the critical factor for the binding between PEP9 and the nanoparticle." @default.
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- W2400686513 date "2005-01-01" @default.
- W2400686513 modified "2023-09-28" @default.
- W2400686513 title "Characterization of Alanine Scanning Mutants of a Peptide Specifically Binding to $TiO_{2}$ Nanoparticles" @default.
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