FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2400703002> ?p ?o ?g. }

• W2400703002 endingPage "C1500" @default.
• W2400703002 startingPage "C1493" @default.
• W2400703002 abstract "It has been suggested that mesangial cells have an osmoregulatory mechanism like that of renal medullary cells, such as intracellular accumulation of polyols in response to hypertonicity. We examined osmoregulatory role of neutral amino acids transported by system A in cultured mesangial cells. The contents of almost all amino acids increased under hypertonic conditions to more than twice the value in isotonic cells. In hypertonic cells, the system A transport activity, measured by Na(+)-dependent 2-(methylamino)isobutyric acid (MeAIB) uptake, was 3.8-fold the uptake in isotonic cells, reaching a maximum 16 h after the switch to hypertonic medium. The response to hypertonicity was the result of an increase in maximal velocity without change in Michaelis constant and was dependent on RNA and protein synthesis. When medium osmolality decreased from hypertonic to isotonic, MeAIB uptake reverted to the isotonic level within 16 h and a large transient efflux of L-proline occurred within 10 min. These results suggest that mesangial cells respond to extracellular hypertonicity by increasing system A transport activity and neutral amino acids can function as compatible osmolytes in mesangial cells." @default.
• W2400703002 created "2016-06-24" @default.
• W2400703002 creator A5000096233 @default.
• W2400703002 creator A5002530228 @default.
• W2400703002 creator A5007669760 @default.
• W2400703002 creator A5011783776 @default.
• W2400703002 creator A5021161768 @default.
• W2400703002 creator A5027899300 @default.
• W2400703002 creator A5090092776 @default.
• W2400703002 date "1994-11-01" @default.
• W2400703002 modified "2023-09-26" @default.
• W2400703002 title "Response to osmotic stimuli in mesangial cells: role of system A transporter" @default.
• W2400703002 cites W1499693439 @default.
• W2400703002 cites W1533221205 @default.
• W2400703002 cites W1568192877 @default.
• W2400703002 cites W1577149434 @default.
• W2400703002 cites W1982831508 @default.
• W2400703002 cites W1986115510 @default.
• W2400703002 cites W1986552094 @default.
• W2400703002 cites W1997634040 @default.
• W2400703002 cites W2006233025 @default.
• W2400703002 cites W2011615614 @default.
• W2400703002 cites W2038517238 @default.
• W2400703002 cites W2059574066 @default.
• W2400703002 cites W2075120289 @default.
• W2400703002 cites W2075302802 @default.
• W2400703002 cites W2079588007 @default.
• W2400703002 cites W2112860230 @default.
• W2400703002 cites W2167382618 @default.
• W2400703002 cites W2168524266 @default.
• W2400703002 doi "https://doi.org/10.1152/ajpcell.1994.267.5.c1493" @default.
• W2400703002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7977710" @default.
• W2400703002 hasPublicationYear "1994" @default.
• W2400703002 type Work @default.
• W2400703002 sameAs 2400703002 @default.
• W2400703002 citedByCount "40" @default.
• W2400703002 countsByYear W24007030022013 @default.
• W2400703002 countsByYear W24007030022014 @default.
• W2400703002 countsByYear W24007030022016 @default.
• W2400703002 countsByYear W24007030022017 @default.
• W2400703002 countsByYear W24007030022018 @default.
• W2400703002 countsByYear W24007030022023 @default.
• W2400703002 crossrefType "journal-article" @default.
• W2400703002 hasAuthorship W2400703002A5000096233 @default.
• W2400703002 hasAuthorship W2400703002A5002530228 @default.
• W2400703002 hasAuthorship W2400703002A5007669760 @default.
• W2400703002 hasAuthorship W2400703002A5011783776 @default.
• W2400703002 hasAuthorship W2400703002A5021161768 @default.
• W2400703002 hasAuthorship W2400703002A5027899300 @default.
• W2400703002 hasAuthorship W2400703002A5090092776 @default.
• W2400703002 hasConcept C104317684 @default.
• W2400703002 hasConcept C117277713 @default.
• W2400703002 hasConcept C12554922 @default.
• W2400703002 hasConcept C126322002 @default.
• W2400703002 hasConcept C127160389 @default.
• W2400703002 hasConcept C129900496 @default.
• W2400703002 hasConcept C134018914 @default.
• W2400703002 hasConcept C149011108 @default.
• W2400703002 hasConcept C185592680 @default.
• W2400703002 hasConcept C28406088 @default.
• W2400703002 hasConcept C515207424 @default.
• W2400703002 hasConcept C55493867 @default.
• W2400703002 hasConcept C71924100 @default.
• W2400703002 hasConcept C77056095 @default.
• W2400703002 hasConcept C79879829 @default.
• W2400703002 hasConcept C86803240 @default.
• W2400703002 hasConcept C95444343 @default.
• W2400703002 hasConceptScore W2400703002C104317684 @default.
• W2400703002 hasConceptScore W2400703002C117277713 @default.
• W2400703002 hasConceptScore W2400703002C12554922 @default.
• W2400703002 hasConceptScore W2400703002C126322002 @default.
• W2400703002 hasConceptScore W2400703002C127160389 @default.
• W2400703002 hasConceptScore W2400703002C129900496 @default.
• W2400703002 hasConceptScore W2400703002C134018914 @default.
• W2400703002 hasConceptScore W2400703002C149011108 @default.
• W2400703002 hasConceptScore W2400703002C185592680 @default.
• W2400703002 hasConceptScore W2400703002C28406088 @default.
• W2400703002 hasConceptScore W2400703002C515207424 @default.
• W2400703002 hasConceptScore W2400703002C55493867 @default.
• W2400703002 hasConceptScore W2400703002C71924100 @default.
• W2400703002 hasConceptScore W2400703002C77056095 @default.
• W2400703002 hasConceptScore W2400703002C79879829 @default.
• W2400703002 hasConceptScore W2400703002C86803240 @default.
• W2400703002 hasConceptScore W2400703002C95444343 @default.
• W2400703002 hasIssue "5" @default.
• W2400703002 hasLocation W24007030021 @default.
• W2400703002 hasLocation W24007030022 @default.
• W2400703002 hasOpenAccess W2400703002 @default.
• W2400703002 hasPrimaryLocation W24007030021 @default.
• W2400703002 hasRelatedWork W1569013596 @default.
• W2400703002 hasRelatedWork W1816636001 @default.
• W2400703002 hasRelatedWork W1968714519 @default.
• W2400703002 hasRelatedWork W2015730525 @default.
• W2400703002 hasRelatedWork W2078868720 @default.
• W2400703002 hasRelatedWork W2085862980 @default.
• W2400703002 hasRelatedWork W2108054829 @default.
• W2400703002 hasRelatedWork W2154012993 @default.
• W2400703002 hasRelatedWork W2405174010 @default.

• next