FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2400716750> ?p ?o ?g. }

• W2400716750 endingPage "588" @default.
• W2400716750 startingPage "585" @default.
• W2400716750 abstract "Platelet-derived growth factor (PDGF) is a mitogen associated with tissue repair, a process involving collagen synthesis and remodelling by interstitial collagenase. This study examines and compares the regulation of interstitial collagenase and collagen gene expression by PDGF-AA and -BB in human fibroblasts. Time-course analysis showed that neither PDGF-AA or -BB had a consistent effect on the expression of pro-alpha 1(I) or pro-alpha 2(I) type-I collagen genes. In contrast, interstitial collagenase gene expression was found to be consistently up-regulated severalfold by PDGF-BB. Enhanced expression of the collagenase gene was not apparently due to up-regulation of its promoter activity in human dermal fibroblasts, as indicated by transient and stable transfection experiments. Unlike PDGF-BB, PDGF-AA did not alter collagenase mRNA levels under low-serum culture conditions. Thus, the biological activities of the PDGF homodimers are different, with PDGF-BB being clearly more potent than PDGF-AA in its regulation of collagenase gene expression." @default.
• W2400716750 created "2016-06-24" @default.
• W2400716750 creator A5011552966 @default.
• W2400716750 creator A5013037823 @default.
• W2400716750 creator A5022391836 @default.
• W2400716750 creator A5063488109 @default.
• W2400716750 creator A5083265128 @default.
• W2400716750 creator A5086562888 @default.
• W2400716750 date "1995-09-01" @default.
• W2400716750 modified "2023-09-25" @default.
• W2400716750 title "Platelet-derived growth factors-AA and -BB regulate collagen and collagenase gene expression differentially in human fibroblasts" @default.
• W2400716750 cites W1489423942 @default.
• W2400716750 cites W1543752796 @default.
• W2400716750 cites W1577422435 @default.
• W2400716750 cites W1965372133 @default.
• W2400716750 cites W1973645860 @default.
• W2400716750 cites W1974790290 @default.
• W2400716750 cites W1977510866 @default.
• W2400716750 cites W1997836176 @default.
• W2400716750 cites W2011374830 @default.
• W2400716750 cites W2012383791 @default.
• W2400716750 cites W2020229999 @default.
• W2400716750 cites W2021890356 @default.
• W2400716750 cites W2032600943 @default.
• W2400716750 cites W2038900950 @default.
• W2400716750 cites W2041168586 @default.
• W2400716750 cites W2044918751 @default.
• W2400716750 cites W2051819610 @default.
• W2400716750 cites W2077077811 @default.
• W2400716750 cites W2079235460 @default.
• W2400716750 cites W2090238172 @default.
• W2400716750 cites W2091960256 @default.
• W2400716750 cites W2141676073 @default.
• W2400716750 cites W2144206181 @default.
• W2400716750 cites W2148371225 @default.
• W2400716750 cites W2158464481 @default.
• W2400716750 cites W2418747844 @default.
• W2400716750 cites W2066918155 @default.
• W2400716750 doi "https://doi.org/10.1042/bj3100585" @default.
• W2400716750 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1135935" @default.
• W2400716750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7654198" @default.
• W2400716750 hasPublicationYear "1995" @default.
• W2400716750 type Work @default.
• W2400716750 sameAs 2400716750 @default.
• W2400716750 citedByCount "32" @default.
• W2400716750 countsByYear W24007167502014 @default.
• W2400716750 countsByYear W24007167502016 @default.
• W2400716750 countsByYear W24007167502017 @default.
• W2400716750 countsByYear W24007167502020 @default.
• W2400716750 countsByYear W24007167502022 @default.
• W2400716750 crossrefType "journal-article" @default.
• W2400716750 hasAuthorship W2400716750A5011552966 @default.
• W2400716750 hasAuthorship W2400716750A5013037823 @default.
• W2400716750 hasAuthorship W2400716750A5022391836 @default.
• W2400716750 hasAuthorship W2400716750A5063488109 @default.
• W2400716750 hasAuthorship W2400716750A5083265128 @default.
• W2400716750 hasAuthorship W2400716750A5086562888 @default.
• W2400716750 hasBestOaLocation W24007167502 @default.
• W2400716750 hasConcept C104317684 @default.
• W2400716750 hasConcept C150194340 @default.
• W2400716750 hasConcept C153911025 @default.
• W2400716750 hasConcept C165864922 @default.
• W2400716750 hasConcept C170493617 @default.
• W2400716750 hasConcept C180361614 @default.
• W2400716750 hasConcept C181199279 @default.
• W2400716750 hasConcept C185592680 @default.
• W2400716750 hasConcept C2775960820 @default.
• W2400716750 hasConcept C2776747403 @default.
• W2400716750 hasConcept C2778394429 @default.
• W2400716750 hasConcept C2781294074 @default.
• W2400716750 hasConcept C54009773 @default.
• W2400716750 hasConcept C55493867 @default.
• W2400716750 hasConcept C86803240 @default.
• W2400716750 hasConcept C95444343 @default.
• W2400716750 hasConceptScore W2400716750C104317684 @default.
• W2400716750 hasConceptScore W2400716750C150194340 @default.
• W2400716750 hasConceptScore W2400716750C153911025 @default.
• W2400716750 hasConceptScore W2400716750C165864922 @default.
• W2400716750 hasConceptScore W2400716750C170493617 @default.
• W2400716750 hasConceptScore W2400716750C180361614 @default.
• W2400716750 hasConceptScore W2400716750C181199279 @default.
• W2400716750 hasConceptScore W2400716750C185592680 @default.
• W2400716750 hasConceptScore W2400716750C2775960820 @default.
• W2400716750 hasConceptScore W2400716750C2776747403 @default.
• W2400716750 hasConceptScore W2400716750C2778394429 @default.
• W2400716750 hasConceptScore W2400716750C2781294074 @default.
• W2400716750 hasConceptScore W2400716750C54009773 @default.
• W2400716750 hasConceptScore W2400716750C55493867 @default.
• W2400716750 hasConceptScore W2400716750C86803240 @default.
• W2400716750 hasConceptScore W2400716750C95444343 @default.
• W2400716750 hasIssue "2" @default.
• W2400716750 hasLocation W24007167501 @default.
• W2400716750 hasLocation W24007167502 @default.
• W2400716750 hasLocation W24007167503 @default.
• W2400716750 hasLocation W24007167504 @default.
• W2400716750 hasOpenAccess W2400716750 @default.
• W2400716750 hasPrimaryLocation W24007167501 @default.
• W2400716750 hasRelatedWork W1920142430 @default.

• next