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- W2400872087 abstract "Dilation of the cervical canal with special mechanical devices causes trauma to the neck of the uterus, especially in women who are pregnant for the 1st time. In order to prevent such traumas, the effect of prostaglandin F2-alpha (PGF2-alpha) on the neck of the uterus when performing abortions during the 1st trimester of pregnancy was studied in 166 women, aged 14-37 years, with terms of pregnancy ranging from 7-12 weeks. The Hungarian pill Enzaprost F, containing 2.5 mg of PGF2 alpha, was used. 7 or 10 Enzaprost F pills were inserted into the cervical canal. Placebo pills were used for the 20-patient control group. The width of the cervical canal was measured with Hegar dilators. Mechanical dilation to 11 mm was carried out as necessary, and abortions were performed by curettage and/or vacuum aspiration. For all of the women under study, pulse, blood pressure, and body temperature were measured and the side effects of PGF2-alpha were recorded. Application of PGF2-alpha softened the tissue of the neck of the uterus and facilitated subsequent mechanical dilation of the cervical canal. In 43 women, no additional dilation was needed. The degree of dilation depended on the procedure used to insert the pills and on the duration of their action. Placebo pills did not dilate the cervical canal. The data confirm that PGF2-alpha directly affects the tissue of the neck of the uterus. Use of Enzaprost F is recommended for intracervical insertion in induced abortions to prevent trauma to the neck of the uterus." @default.
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- W2400872087 date "1985-03-01" @default.
- W2400872087 modified "2023-09-23" @default.
- W2400872087 title "[Use of prostaglandin F2 alpha for dilating the cervical canal in performing an abortion]." @default.
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