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- W2400962823 abstract "A42-year-old white man was referred to our center by his primary care physician for symptoms of chronic diarrhea associated with cramping, abdominal pain, and flatulence. The patient had chronic gastroesophageal reflux disease (GERD) and had been taking omeprazole 20 mg twice daily for the past 12 years.A colonoscopy and esophagogastroduodenoscopy (EGD) were performed for symptom workup. The colonoscopy revealed no significant findings. The EGD showed approximately 30 large pedunculated polyps in the gastric body and fundus (Figure 1). The size of the largest polyp was approximately 2 cm. Biopsies of the polyps were obtained with cold forceps. Histologic examination of the specimens showed multiple fragments of fundic gland mucosa with occasional dilated glands. Based on the EGD and histology, the patient was diagnosed with fundic gland polyps (FGPs). The most likely etiology was thought to be the prolonged use of proton pump inhibitor (PPI) therapy. Therefore, omeprazole was discontinued, and ranitidine 150 mg bid was started. A repeat EGD performed 5 months later showed a significant decrease in the size of the polyps and no polyps were pedunculated (Figure 2). Pathology of the biopsy sample confirmed the presence of FGPs with no evidence of malignancy.Figure 1.An endoscopic image of fundic gland polyps while the patient was on omeprazole.Figure 2.An endoscopic image of fundic gland polyps after the discontinuation of omeprazole." @default.
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- W2400962823 date "2016-03-01" @default.
- W2400962823 modified "2023-10-18" @default.
- W2400962823 title "Large Fundic Gland Polyps in the Stomach." @default.
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