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• W2401133735 abstract "Acute kidney injury after cardiac surgery with cardiopulmonary bypass is a common and serious complication and it is associated with increased morbidity and mortality. Diagnosis of acute kidney injury is based on the serum creatinine levels which rise several hours to days after the initial injury. Thus, novel biomarkers that will enable faster diagnosis are needed in clinical practice. There are numerous urine and serum proteins that indicate kidney injury and are under extensive research. Despite promising basic research results and assembled data, which indicate superiority of some biomarkers to creatinine, we are still awaiting clinical application. Ostre uszkodzenie nerek po operacji kardiochirurgicznej z użyciem bypassu sercowo-płucnego to częsta i poważna komplikacja powiązana z wyższym ryzykiem powikłań i śmiertelnością. Rozpoznania ostrego uszkodzenia nerek dokonuje się na podstawie stężenia kreatyniny w surowicy, które wzrasta w ciągu kilku godzin do kilku dni po początkowym urazie. Dlatego też w praktyce klinicznej konieczne są nowe markery umożliwiające szybszą diagnozę. Istnieje wiele rodzajów białek, których obecność w moczu i surowicy wskazuje na uszkodzenie nerek. Prowadzone są nad nimi intensywne badania. Pomimo obiecujących wyników badań wstępnych i zebrania danych sugerujących wyższość niektórych biomarkerów w porównaniu z kreatyniną, wciąż czekamy na ich zastosowanie kliniczne." @default.
• W2401133735 created "2016-06-24" @default.
• W2401133735 creator A5008165597 @default.
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• W2401133735 date "2016-01-01" @default.
• W2401133735 modified "2023-09-30" @default.
• W2401133735 title "Novel biomarkers for early diagnosis of acute kidney injury after cardiac surgery in adults" @default.
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• W2401133735 doi "https://doi.org/10.5114/kitp.2016.58962" @default.
• W2401133735 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4860432" @default.
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