FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2401337239> ?p ?o ?g. }

• W2401337239 endingPage "2015" @default.
• W2401337239 startingPage "00106" @default.
• W2401337239 abstract "Asthma management guidelines recommend adding a long-acting β2-agonist (LABA) or increasing the dose of inhaled corticosteroid (ICS) as step-up therapy for patients with uncontrolled asthma on ICS monotherapy. However, it is uncertain which option works best, which ICS particle size is most effective, and whether LABA should be administered by separate or combination inhalers. This historical, matched cohort study compared asthma-related outcomes for patients (aged 12-80 years) prescribed step-up therapy as a ≥50% extrafine ICS dose increase or add-on LABA, via either a separate inhaler or a fine-particle ICS/LABA fixed-dose combination (FDC) inhaler. Risk-domain asthma control was the primary end-point in comparisons of cohorts matched for asthma severity and control during the baseline year. After 1:2 cohort matching, the increased extrafine ICS versus separate ICS+LABA cohorts included 3232 and 6464 patients, respectively, and the fine-particle ICS/LABA FDC versus separate ICS+LABA cohorts included 7529 and 15 058 patients, respectively (overall mean age 42 years; 61-62% females). Over one outcome year, adjusted OR (95% CI) for achieving asthma control were 1.25 (1.13-1.38) for increased ICS versus separate ICS+LABA and 1.06 (1.05-1.09) for ICS/LABA FDC versus separate ICS+LABA. For patients with asthma, increased dose of extrafine-particle ICS, or add-on LABA via ICS/LABA combination inhaler, is associated with significantly better outcomes than ICS+LABA via separate inhalers." @default.
• W2401337239 created "2016-06-24" @default.
• W2401337239 creator A5025316834 @default.
• W2401337239 creator A5030603878 @default.
• W2401337239 creator A5031762844 @default.
• W2401337239 creator A5033749081 @default.
• W2401337239 creator A5035054463 @default.
• W2401337239 creator A5036290773 @default.
• W2401337239 creator A5044705183 @default.
• W2401337239 creator A5046059982 @default.
• W2401337239 creator A5052175038 @default.
• W2401337239 creator A5060011688 @default.
• W2401337239 creator A5068913631 @default.
• W2401337239 date "2016-04-01" @default.
• W2401337239 modified "2023-09-30" @default.
• W2401337239 title "Add-on LABA in a separate inhaler as asthma step-up therapy <i>versus</i> increased dose of ICS or ICS/LABA combination inhaler" @default.
• W2401337239 cites W1782227377 @default.
• W2401337239 cites W1962391690 @default.
• W2401337239 cites W1964815067 @default.
• W2401337239 cites W1965301392 @default.
• W2401337239 cites W1968405264 @default.
• W2401337239 cites W1976797956 @default.
• W2401337239 cites W1982191652 @default.
• W2401337239 cites W2013037468 @default.
• W2401337239 cites W2015366993 @default.
• W2401337239 cites W2017385258 @default.
• W2401337239 cites W2020350342 @default.
• W2401337239 cites W2032620602 @default.
• W2401337239 cites W2035216610 @default.
• W2401337239 cites W2040211145 @default.
• W2401337239 cites W2053351348 @default.
• W2401337239 cites W2058979515 @default.
• W2401337239 cites W2059121696 @default.
• W2401337239 cites W2066065331 @default.
• W2401337239 cites W2070615979 @default.
• W2401337239 cites W2098633046 @default.
• W2401337239 cites W2102987799 @default.
• W2401337239 cites W2105117973 @default.
• W2401337239 cites W2114547039 @default.
• W2401337239 cites W2119091391 @default.
• W2401337239 cites W2121545123 @default.
• W2401337239 cites W2133162613 @default.
• W2401337239 cites W2133893447 @default.
• W2401337239 cites W2139291708 @default.
• W2401337239 cites W2148583736 @default.
• W2401337239 cites W2152569940 @default.
• W2401337239 cites W2153001711 @default.
• W2401337239 cites W2159397032 @default.
• W2401337239 cites W2161800479 @default.
• W2401337239 cites W2166817545 @default.
• W2401337239 cites W2167713965 @default.
• W2401337239 cites W2195424142 @default.
• W2401337239 cites W2331287401 @default.
• W2401337239 cites W2601675613 @default.
• W2401337239 cites W4229553561 @default.
• W2401337239 doi "https://doi.org/10.1183/23120541.00106-2015" @default.
• W2401337239 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5005184" @default.
• W2401337239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27730200" @default.
• W2401337239 hasPublicationYear "2016" @default.
• W2401337239 type Work @default.
• W2401337239 sameAs 2401337239 @default.
• W2401337239 citedByCount "10" @default.
• W2401337239 countsByYear W24013372392017 @default.
• W2401337239 countsByYear W24013372392018 @default.
• W2401337239 countsByYear W24013372392019 @default.
• W2401337239 countsByYear W24013372392020 @default.
• W2401337239 countsByYear W24013372392021 @default.
• W2401337239 countsByYear W24013372392022 @default.
• W2401337239 crossrefType "journal-article" @default.
• W2401337239 hasAuthorship W2401337239A5025316834 @default.
• W2401337239 hasAuthorship W2401337239A5030603878 @default.
• W2401337239 hasAuthorship W2401337239A5031762844 @default.
• W2401337239 hasAuthorship W2401337239A5033749081 @default.
• W2401337239 hasAuthorship W2401337239A5035054463 @default.
• W2401337239 hasAuthorship W2401337239A5036290773 @default.
• W2401337239 hasAuthorship W2401337239A5044705183 @default.
• W2401337239 hasAuthorship W2401337239A5046059982 @default.
• W2401337239 hasAuthorship W2401337239A5052175038 @default.
• W2401337239 hasAuthorship W2401337239A5060011688 @default.
• W2401337239 hasAuthorship W2401337239A5068913631 @default.
• W2401337239 hasBestOaLocation W24013372391 @default.
• W2401337239 hasConcept C126322002 @default.
• W2401337239 hasConcept C2776042228 @default.
• W2401337239 hasConcept C2776804153 @default.
• W2401337239 hasConcept C2776999253 @default.
• W2401337239 hasConcept C2780261241 @default.
• W2401337239 hasConcept C3018080372 @default.
• W2401337239 hasConcept C71924100 @default.
• W2401337239 hasConcept C72563966 @default.
• W2401337239 hasConceptScore W2401337239C126322002 @default.
• W2401337239 hasConceptScore W2401337239C2776042228 @default.
• W2401337239 hasConceptScore W2401337239C2776804153 @default.
• W2401337239 hasConceptScore W2401337239C2776999253 @default.
• W2401337239 hasConceptScore W2401337239C2780261241 @default.
• W2401337239 hasConceptScore W2401337239C3018080372 @default.
• W2401337239 hasConceptScore W2401337239C71924100 @default.
• W2401337239 hasConceptScore W2401337239C72563966 @default.
• W2401337239 hasFunder F4320308970 @default.

• next