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• W2401395957 abstract "The onset of testicular pathology in the rat and possible recovery over an 8-week period were evaluated after the administration of up to 20 daily oral doses of bis(2-methoxyethyl) ether (diglyme) at 5.1 mmol/kg bw (684 mg/kg bw). Primary and secondary spermatocyte degeneration and spermatidic giant cells were observed after six to eight treatments. In addition, the testes-to-body weight ratio was significantly reduced by the tenth day of treatment and continued to be depressed eight weeks after discontinuation of the treatment. Testicular LDH-X activity, a pachytene spermatocyte marker enzyme, was significantly decreased in animals by the eighteenth day of treatment with diglyme." @default.
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• W2401395957 date "1985-12-01" @default.
• W2401395957 modified "2023-10-09" @default.
• W2401395957 title "Testicular Effects of Bis (2-Methoxyethyl) Ether in the Adult Male Rat" @default.
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• W2401395957 doi "https://doi.org/10.1177/074823378900500615" @default.
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