Matches in SemOpenAlex for { <https://semopenalex.org/work/W2401508737> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2401508737 endingPage "798" @default.
- W2401508737 startingPage "793" @default.
- W2401508737 abstract "Testicular responsiveness to a single dose of human chorionic gonadotropin was studied in five normal men before and during short-term treatment with an aromatization inhibitor, testolactone (TL). TL alone resulted in significant increases in the serum concentrations of progesterone, 17-hydroxyprogesterone, 17-hydroxypregnenolone, dehydroepiandrosterone, androstenedione, and the sulfate conjugates of pregnenolone, 17-hydroxypregnenolone and testosterone (T). Concentrations of 5-androstene-3 beta, 17 beta-diol and T remained unchanged, and those of estradiol (E2) decreased. TL had no major influence on serum luteinizing hormone, follicle-stimulating hormone, prolactin, or sex-hormone-binding globulin concentrations. During TL administration, human chorionic gonadotropin stimulation led to a significantly decreased E2 response, but the T response was unchanged. Alleviation of an inhibitory influence of E2 on the steroidogenic enzymes, especially 17,20-desmolase, was probably the reason behind the increased synthesis of several T precursors. In addition, TL appeared to have an inhibitory influence on the 17 beta-reduction of T precursors. TL resulted in increased serum concentrations of some steroid sulfates, but the mechanism of this effect remains unclear." @default.
- W2401508737 created "2016-06-24" @default.
- W2401508737 creator A5025017080 @default.
- W2401508737 creator A5035333722 @default.
- W2401508737 creator A5049484171 @default.
- W2401508737 creator A5089464396 @default.
- W2401508737 date "1985-05-01" @default.
- W2401508737 modified "2023-10-14" @default.
- W2401508737 title "Short-term effects of testolactone on human testicular steroid production and on the response to human chorionic gonadotropin" @default.
- W2401508737 cites W1967975371 @default.
- W2401508737 cites W1968759596 @default.
- W2401508737 cites W1989668413 @default.
- W2401508737 cites W1993364496 @default.
- W2401508737 cites W2000569656 @default.
- W2401508737 cites W2022169262 @default.
- W2401508737 cites W2026977179 @default.
- W2401508737 cites W2030305135 @default.
- W2401508737 cites W2030698496 @default.
- W2401508737 cites W2035890891 @default.
- W2401508737 cites W2052055385 @default.
- W2401508737 cites W2066998567 @default.
- W2401508737 cites W2132450885 @default.
- W2401508737 cites W2150543906 @default.
- W2401508737 cites W2162134480 @default.
- W2401508737 cites W2162613596 @default.
- W2401508737 cites W2171142088 @default.
- W2401508737 cites W2433967518 @default.
- W2401508737 doi "https://doi.org/10.1016/s0015-0282(16)48568-7" @default.
- W2401508737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3922804" @default.
- W2401508737 hasPublicationYear "1985" @default.
- W2401508737 type Work @default.
- W2401508737 sameAs 2401508737 @default.
- W2401508737 citedByCount "4" @default.
- W2401508737 countsByYear W24015087372023 @default.
- W2401508737 crossrefType "journal-article" @default.
- W2401508737 hasAuthorship W2401508737A5025017080 @default.
- W2401508737 hasAuthorship W2401508737A5035333722 @default.
- W2401508737 hasAuthorship W2401508737A5049484171 @default.
- W2401508737 hasAuthorship W2401508737A5089464396 @default.
- W2401508737 hasConcept C126322002 @default.
- W2401508737 hasConcept C134018914 @default.
- W2401508737 hasConcept C185592680 @default.
- W2401508737 hasConcept C24998067 @default.
- W2401508737 hasConcept C2775948956 @default.
- W2401508737 hasConcept C2776683971 @default.
- W2401508737 hasConcept C2776992908 @default.
- W2401508737 hasConcept C2777911890 @default.
- W2401508737 hasConcept C2778575703 @default.
- W2401508737 hasConcept C2778782382 @default.
- W2401508737 hasConcept C2779064019 @default.
- W2401508737 hasConcept C2779279991 @default.
- W2401508737 hasConcept C2780193516 @default.
- W2401508737 hasConcept C2780902042 @default.
- W2401508737 hasConcept C71315377 @default.
- W2401508737 hasConcept C71924100 @default.
- W2401508737 hasConcept C86803240 @default.
- W2401508737 hasConceptScore W2401508737C126322002 @default.
- W2401508737 hasConceptScore W2401508737C134018914 @default.
- W2401508737 hasConceptScore W2401508737C185592680 @default.
- W2401508737 hasConceptScore W2401508737C24998067 @default.
- W2401508737 hasConceptScore W2401508737C2775948956 @default.
- W2401508737 hasConceptScore W2401508737C2776683971 @default.
- W2401508737 hasConceptScore W2401508737C2776992908 @default.
- W2401508737 hasConceptScore W2401508737C2777911890 @default.
- W2401508737 hasConceptScore W2401508737C2778575703 @default.
- W2401508737 hasConceptScore W2401508737C2778782382 @default.
- W2401508737 hasConceptScore W2401508737C2779064019 @default.
- W2401508737 hasConceptScore W2401508737C2779279991 @default.
- W2401508737 hasConceptScore W2401508737C2780193516 @default.
- W2401508737 hasConceptScore W2401508737C2780902042 @default.
- W2401508737 hasConceptScore W2401508737C71315377 @default.
- W2401508737 hasConceptScore W2401508737C71924100 @default.
- W2401508737 hasConceptScore W2401508737C86803240 @default.
- W2401508737 hasIssue "5" @default.
- W2401508737 hasLocation W24015087371 @default.
- W2401508737 hasLocation W24015087372 @default.
- W2401508737 hasOpenAccess W2401508737 @default.
- W2401508737 hasPrimaryLocation W24015087371 @default.
- W2401508737 hasRelatedWork W1987914672 @default.
- W2401508737 hasRelatedWork W1996631864 @default.
- W2401508737 hasRelatedWork W2010765037 @default.
- W2401508737 hasRelatedWork W2035245144 @default.
- W2401508737 hasRelatedWork W2050826448 @default.
- W2401508737 hasRelatedWork W2100202028 @default.
- W2401508737 hasRelatedWork W2117540046 @default.
- W2401508737 hasRelatedWork W2122241486 @default.
- W2401508737 hasRelatedWork W2394390748 @default.
- W2401508737 hasRelatedWork W2418722780 @default.
- W2401508737 hasVolume "43" @default.
- W2401508737 isParatext "false" @default.
- W2401508737 isRetracted "false" @default.
- W2401508737 magId "2401508737" @default.
- W2401508737 workType "article" @default.