FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2401609737> ?p ?o ?g. }

• W2401609737 endingPage "13" @default.
• W2401609737 startingPage "1" @default.
• W2401609737 abstract "Hypercholesterolemia, induced by a cholesterol-enriched diet, is associated with distinctive modifications in the serum lipoproteins of a variety of species. Present in the serum of these animals are several classes of lipoproteins enriched in cholesteryl esters and apolipoprotein E. To investigate the role of intestinal lipoprotein synthesis in diet-induced hypercholesterolemia, we characterized nascent lipoproteins retrieved from Golgi apparatus-rich fractions of intestinal epithelial cells from chow-fed control and hypercholesterolemic rats. To eliminate chylomicrons from the preparations, rats were fasted overnight prior to the experiments. Golgi very low density lipoproteins (d less than 1.006 g/ml) from control rats were triglyceride-rich lipoproteins that migrated slightly slower than pre-beta migrating serum very low density lipoproteins. These particles contained apoproteins B-240, A-IV, and A-I. Golgi very low density lipoproteins from hypercholesterolemic rats were likewise triglyceride-rich lipoproteins migrating electrophoretically like control Golgi very low density lipoproteins and they contained apoproteins B-240, A-IV, and A-I. However, these latter particles contained less triglyceride and more cholesterol compared to control Golgi very low density lipoproteins. In addition, by radioisotope incorporation studies, Golgi very low density lipoproteins from hypercholesterolemic rats contained relatively more apoprotein A-IV (21.6 vs. 11.0%) and less apoprotein B-240 (17.0 vs. 27.0%) than found in control Golgi very low density lipoproteins. Approximately 60% of the total apoprotein radioactivity was found in apoprotein A-I in both preparations. We conclude that intestinal lipoprotein synthesis is modified by diet-induced hypercholesterolemia. The significance of these modifications with respect to the marked hypercholesterolemia observed in these animals remains to be determined." @default.
• W2401609737 created "2016-06-24" @default.
• W2401609737 creator A5007411761 @default.
• W2401609737 creator A5020208355 @default.
• W2401609737 creator A5041502509 @default.
• W2401609737 creator A5049717320 @default.
• W2401609737 date "1984-01-01" @default.
• W2401609737 modified "2023-09-26" @default.
• W2401609737 title "Intestinal lipoprotein synthesis. Comparison of nascent Golgi lipoproteins from chow-fed and hypercholesterolemic rats." @default.
• W2401609737 cites W1513897103 @default.
• W2401609737 cites W1514706775 @default.
• W2401609737 cites W1569439639 @default.
• W2401609737 cites W1893943578 @default.
• W2401609737 cites W1967634369 @default.
• W2401609737 cites W1976303136 @default.
• W2401609737 cites W1979876641 @default.
• W2401609737 cites W2009504999 @default.
• W2401609737 cites W2009792148 @default.
• W2401609737 cites W2017722922 @default.
• W2401609737 cites W2020765844 @default.
• W2401609737 cites W2025093775 @default.
• W2401609737 cites W2034603293 @default.
• W2401609737 cites W2083353030 @default.
• W2401609737 cites W2100837269 @default.
• W2401609737 cites W2127911529 @default.
• W2401609737 cites W2135503869 @default.
• W2401609737 cites W2142596760 @default.
• W2401609737 cites W2158210244 @default.
• W2401609737 cites W2168224634 @default.
• W2401609737 cites W2181601607 @default.
• W2401609737 cites W2181930845 @default.
• W2401609737 cites W2184182369 @default.
• W2401609737 cites W2184949828 @default.
• W2401609737 cites W2185120011 @default.
• W2401609737 cites W2249523505 @default.
• W2401609737 cites W2340252332 @default.
• W2401609737 cites W2341579124 @default.
• W2401609737 cites W2346779575 @default.
• W2401609737 cites W2411452313 @default.
• W2401609737 cites W2412274443 @default.
• W2401609737 cites W4293247451 @default.
• W2401609737 doi "https://doi.org/10.1016/s0022-2275(20)37847-0" @default.
• W2401609737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6707517" @default.
• W2401609737 hasPublicationYear "1984" @default.
• W2401609737 type Work @default.
• W2401609737 sameAs 2401609737 @default.
• W2401609737 citedByCount "36" @default.
• W2401609737 crossrefType "journal-article" @default.
• W2401609737 hasAuthorship W2401609737A5007411761 @default.
• W2401609737 hasAuthorship W2401609737A5020208355 @default.
• W2401609737 hasAuthorship W2401609737A5041502509 @default.
• W2401609737 hasAuthorship W2401609737A5049717320 @default.
• W2401609737 hasBestOaLocation W24016097371 @default.
• W2401609737 hasConcept C119062480 @default.
• W2401609737 hasConcept C126322002 @default.
• W2401609737 hasConcept C134018914 @default.
• W2401609737 hasConcept C158617107 @default.
• W2401609737 hasConcept C185592680 @default.
• W2401609737 hasConcept C2778163477 @default.
• W2401609737 hasConcept C2780072125 @default.
• W2401609737 hasConcept C55493867 @default.
• W2401609737 hasConcept C71924100 @default.
• W2401609737 hasConcept C86803240 @default.
• W2401609737 hasConcept C95444343 @default.
• W2401609737 hasConceptScore W2401609737C119062480 @default.
• W2401609737 hasConceptScore W2401609737C126322002 @default.
• W2401609737 hasConceptScore W2401609737C134018914 @default.
• W2401609737 hasConceptScore W2401609737C158617107 @default.
• W2401609737 hasConceptScore W2401609737C185592680 @default.
• W2401609737 hasConceptScore W2401609737C2778163477 @default.
• W2401609737 hasConceptScore W2401609737C2780072125 @default.
• W2401609737 hasConceptScore W2401609737C55493867 @default.
• W2401609737 hasConceptScore W2401609737C71924100 @default.
• W2401609737 hasConceptScore W2401609737C86803240 @default.
• W2401609737 hasConceptScore W2401609737C95444343 @default.
• W2401609737 hasIssue "1" @default.
• W2401609737 hasLocation W24016097371 @default.
• W2401609737 hasOpenAccess W2401609737 @default.
• W2401609737 hasPrimaryLocation W24016097371 @default.
• W2401609737 hasRelatedWork W1966834268 @default.
• W2401609737 hasRelatedWork W1972175381 @default.
• W2401609737 hasRelatedWork W2005998106 @default.
• W2401609737 hasRelatedWork W2019813684 @default.
• W2401609737 hasRelatedWork W2032958076 @default.
• W2401609737 hasRelatedWork W2035331946 @default.
• W2401609737 hasRelatedWork W2075372262 @default.
• W2401609737 hasRelatedWork W2166236611 @default.
• W2401609737 hasRelatedWork W2168843442 @default.
• W2401609737 hasRelatedWork W4242761889 @default.
• W2401609737 hasVolume "25" @default.
• W2401609737 isParatext "false" @default.
• W2401609737 isRetracted "false" @default.
• W2401609737 magId "2401609737" @default.
• W2401609737 workType "article" @default.