Matches in SemOpenAlex for { <https://semopenalex.org/work/W2401631784> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2401631784 endingPage "S7" @default.
- W2401631784 startingPage "S4" @default.
- W2401631784 abstract "The epidemiology, costs, and comorbidities associated with atherosclerosis and the role of newer antiplatelet agents are reviewed. Cardiovascular disease is the leading cause of death in the United States. More than 60 million Americans have one or more types of cardiovascular disease. The total annual cost of coronary heart disease has been estimated at $95 billion. Patients with an existing atherosclerotic disease in one vascular bed are at high risk of having an ischemic vascular event in the same or another vascular bed. Peripheral arterial disease is a strong marker for underlying cerebrovascular and cardiovascular disease. The common link among these diseases is atherosclerosis leading to atherothrombosis. Platelets play an integral role in atherosclerosis and the formation of arterial thrombus as well as in subsequent acute events such as ischemic stroke, myocardial infarction, and vascular death. Arterial thrombosis can be mediated by shear-stress-induced platelet aggregation. Currently, only one third to one half of all eligible patients with stroke, myocardial infarction, or peripheral arterial disease receive antiplatelet therapy. Thienopyridines such as ticlopidine and clopidogrel are effective inhibitors of shear-stress-induced and endothelial-injury-induced platelet aggregation. Advances in antiplatelet therapy provide an opportunity to use newer antiplatelet agents in the prevention of atherosclerosis-related morbidity and mortality; therapeutic approaches should be directed toward recognizing atherosclerosis as a generalized disease process and preventing ischemic events in multiple vascular beds." @default.
- W2401631784 created "2016-06-24" @default.
- W2401631784 creator A5024089965 @default.
- W2401631784 creator A5076151526 @default.
- W2401631784 date "1998-10-01" @default.
- W2401631784 modified "2023-10-18" @default.
- W2401631784 title "Atherosclerosis: A unifying disorder with diverse manifestations" @default.
- W2401631784 doi "https://doi.org/10.1093/ajhp/55.suppl_1.s4" @default.
- W2401631784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9784796" @default.
- W2401631784 hasPublicationYear "1998" @default.
- W2401631784 type Work @default.
- W2401631784 sameAs 2401631784 @default.
- W2401631784 citedByCount "21" @default.
- W2401631784 countsByYear W24016317842014 @default.
- W2401631784 countsByYear W24016317842019 @default.
- W2401631784 countsByYear W24016317842022 @default.
- W2401631784 crossrefType "journal-article" @default.
- W2401631784 hasAuthorship W2401631784A5024089965 @default.
- W2401631784 hasAuthorship W2401631784A5076151526 @default.
- W2401631784 hasBestOaLocation W24016317841 @default.
- W2401631784 hasConcept C126322002 @default.
- W2401631784 hasConcept C127413603 @default.
- W2401631784 hasConcept C164705383 @default.
- W2401631784 hasConcept C2777466421 @default.
- W2401631784 hasConcept C2777849778 @default.
- W2401631784 hasConcept C2778905298 @default.
- W2401631784 hasConcept C2779134260 @default.
- W2401631784 hasConcept C2780645631 @default.
- W2401631784 hasConcept C2780868729 @default.
- W2401631784 hasConcept C2781362458 @default.
- W2401631784 hasConcept C29374701 @default.
- W2401631784 hasConcept C500558357 @default.
- W2401631784 hasConcept C71924100 @default.
- W2401631784 hasConcept C78519656 @default.
- W2401631784 hasConceptScore W2401631784C126322002 @default.
- W2401631784 hasConceptScore W2401631784C127413603 @default.
- W2401631784 hasConceptScore W2401631784C164705383 @default.
- W2401631784 hasConceptScore W2401631784C2777466421 @default.
- W2401631784 hasConceptScore W2401631784C2777849778 @default.
- W2401631784 hasConceptScore W2401631784C2778905298 @default.
- W2401631784 hasConceptScore W2401631784C2779134260 @default.
- W2401631784 hasConceptScore W2401631784C2780645631 @default.
- W2401631784 hasConceptScore W2401631784C2780868729 @default.
- W2401631784 hasConceptScore W2401631784C2781362458 @default.
- W2401631784 hasConceptScore W2401631784C29374701 @default.
- W2401631784 hasConceptScore W2401631784C500558357 @default.
- W2401631784 hasConceptScore W2401631784C71924100 @default.
- W2401631784 hasConceptScore W2401631784C78519656 @default.
- W2401631784 hasIssue "suppl_1" @default.
- W2401631784 hasLocation W24016317841 @default.
- W2401631784 hasLocation W24016317842 @default.
- W2401631784 hasOpenAccess W2401631784 @default.
- W2401631784 hasPrimaryLocation W24016317841 @default.
- W2401631784 hasRelatedWork W1949370008 @default.
- W2401631784 hasRelatedWork W1977401059 @default.
- W2401631784 hasRelatedWork W200356558 @default.
- W2401631784 hasRelatedWork W2005659418 @default.
- W2401631784 hasRelatedWork W2087820646 @default.
- W2401631784 hasRelatedWork W2171917118 @default.
- W2401631784 hasRelatedWork W2262799977 @default.
- W2401631784 hasRelatedWork W2377879227 @default.
- W2401631784 hasRelatedWork W4298277510 @default.
- W2401631784 hasRelatedWork W83485457 @default.
- W2401631784 hasVolume "55" @default.
- W2401631784 isParatext "false" @default.
- W2401631784 isRetracted "false" @default.
- W2401631784 magId "2401631784" @default.
- W2401631784 workType "article" @default.