Matches in SemOpenAlex for { <https://semopenalex.org/work/W2401998002> ?p ?o ?g. }
- W2401998002 endingPage "106" @default.
- W2401998002 startingPage "95" @default.
- W2401998002 abstract "Sympathovagal imbalance contributes to progressive worsening of HF (HF) and is associated with untoward clinical outcomes. Based on compelling pre-clinical studies which supported the role of autonomic modulation in HF models, a series of clinical studies were initiated using spinal cord stimulation (SCS), vagus nerve stimulation (VNS) and baroreceptor activation therapy (BAT) in patients with HF with a reduced ejection fraction (HFrEF). While the phase II studies with BAT remain encouraging, the larger clinical studies with SCS and VNS have yielded disappointing results. Here we will focus on the pre-clinical studies that supported the role of neuromodulation in the failing heart, as well provide a critical review of the recent clinical trials that have sought to modulate autonomic tone in HF patients. This review will conclude with an analysis of some of the difficulties in translating device-based modulation of the autonomic nervous from pre-clinical models into successful clinical trials, as well as provide suggestions for how to move the field of neuromodulation forward." @default.
- W2401998002 created "2016-06-24" @default.
- W2401998002 creator A5076497318 @default.
- W2401998002 creator A5085493348 @default.
- W2401998002 date "2016-04-01" @default.
- W2401998002 modified "2023-09-28" @default.
- W2401998002 title "Neuromodulation of the Failing Heart" @default.
- W2401998002 cites W1482118302 @default.
- W2401998002 cites W1488299655 @default.
- W2401998002 cites W1509413483 @default.
- W2401998002 cites W155312217 @default.
- W2401998002 cites W1883770455 @default.
- W2401998002 cites W1965036361 @default.
- W2401998002 cites W1979085995 @default.
- W2401998002 cites W1986779667 @default.
- W2401998002 cites W1988335417 @default.
- W2401998002 cites W1988338975 @default.
- W2401998002 cites W1989214663 @default.
- W2401998002 cites W1990039263 @default.
- W2401998002 cites W1995078408 @default.
- W2401998002 cites W1995525413 @default.
- W2401998002 cites W2003252502 @default.
- W2401998002 cites W2003517127 @default.
- W2401998002 cites W2007143131 @default.
- W2401998002 cites W2011248940 @default.
- W2401998002 cites W2013634899 @default.
- W2401998002 cites W2014779151 @default.
- W2401998002 cites W2019131544 @default.
- W2401998002 cites W2022775752 @default.
- W2401998002 cites W2025043271 @default.
- W2401998002 cites W2033991301 @default.
- W2401998002 cites W2049381826 @default.
- W2401998002 cites W2059188992 @default.
- W2401998002 cites W2068884498 @default.
- W2401998002 cites W2074217022 @default.
- W2401998002 cites W2077490419 @default.
- W2401998002 cites W2080671217 @default.
- W2401998002 cites W2103596313 @default.
- W2401998002 cites W2109454934 @default.
- W2401998002 cites W2116095873 @default.
- W2401998002 cites W2120723181 @default.
- W2401998002 cites W2121278286 @default.
- W2401998002 cites W2122749049 @default.
- W2401998002 cites W2123181530 @default.
- W2401998002 cites W2130417099 @default.
- W2401998002 cites W2145912168 @default.
- W2401998002 cites W2160216437 @default.
- W2401998002 cites W2161092721 @default.
- W2401998002 cites W2170481101 @default.
- W2401998002 cites W2195581844 @default.
- W2401998002 cites W2269782268 @default.
- W2401998002 cites W2337818477 @default.
- W2401998002 cites W2546883271 @default.
- W2401998002 cites W2913008332 @default.
- W2401998002 doi "https://doi.org/10.1016/j.jacbts.2016.03.004" @default.
- W2401998002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4978351" @default.
- W2401998002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27525317" @default.
- W2401998002 hasPublicationYear "2016" @default.
- W2401998002 type Work @default.
- W2401998002 sameAs 2401998002 @default.
- W2401998002 citedByCount "38" @default.
- W2401998002 countsByYear W24019980022016 @default.
- W2401998002 countsByYear W24019980022017 @default.
- W2401998002 countsByYear W24019980022018 @default.
- W2401998002 countsByYear W24019980022019 @default.
- W2401998002 countsByYear W24019980022020 @default.
- W2401998002 countsByYear W24019980022021 @default.
- W2401998002 countsByYear W24019980022022 @default.
- W2401998002 countsByYear W24019980022023 @default.
- W2401998002 crossrefType "journal-article" @default.
- W2401998002 hasAuthorship W2401998002A5076497318 @default.
- W2401998002 hasAuthorship W2401998002A5085493348 @default.
- W2401998002 hasBestOaLocation W24019980021 @default.
- W2401998002 hasConcept C126322002 @default.
- W2401998002 hasConcept C15744967 @default.
- W2401998002 hasConcept C164705383 @default.
- W2401998002 hasConcept C169760540 @default.
- W2401998002 hasConcept C24998067 @default.
- W2401998002 hasConcept C2777372248 @default.
- W2401998002 hasConcept C2777953023 @default.
- W2401998002 hasConcept C2778198053 @default.
- W2401998002 hasConcept C2778542668 @default.
- W2401998002 hasConcept C2779134260 @default.
- W2401998002 hasConcept C2779734285 @default.
- W2401998002 hasConcept C2780087125 @default.
- W2401998002 hasConcept C2780375056 @default.
- W2401998002 hasConcept C2781404750 @default.
- W2401998002 hasConcept C2984781990 @default.
- W2401998002 hasConcept C535046627 @default.
- W2401998002 hasConcept C71924100 @default.
- W2401998002 hasConcept C79752029 @default.
- W2401998002 hasConcept C84393581 @default.
- W2401998002 hasConceptScore W2401998002C126322002 @default.
- W2401998002 hasConceptScore W2401998002C15744967 @default.
- W2401998002 hasConceptScore W2401998002C164705383 @default.
- W2401998002 hasConceptScore W2401998002C169760540 @default.
- W2401998002 hasConceptScore W2401998002C24998067 @default.
- W2401998002 hasConceptScore W2401998002C2777372248 @default.