FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2402234900> ?p ?o ?g. }

• W2402234900 endingPage "411" @default.
• W2402234900 startingPage "407" @default.
• W2402234900 abstract "Abstract The purpose of this investigation was to test whether the generation of oxygen radicals is required for the cytotoxic activity of human monocytes. The cytotoxic activity of human monocytes was measured as the capacity to lyse, in vitro, human red cells sensitized with non-complement-binding IgG anti-D alloanti-bodies. Lysis was determined by measuring 51Cr release from the red cells. Studies were performed with monocytes from patients with chronic granulomatous disease (CGD). In contrast with normal neutrophils, phagocytosing neutrophils from these patients are unable to generate oxygen radicals, hydrogen peroxide, or singlet oxygen. We found that monocytes from CGD patients were similarly incapable of generating these reactive oxygen species during phagocytosis. This indicates that, like neutrophils, monocytes from CGD patients are defective in the generation of activated oxygen products. Despite this defect, monocytes from CGD patients displayed a normal cytotoxic activity towards sensitized red cells. In addition, neither scavengers of superoxide, hydrogen peroxide, hydroxyl radicals, or singlet oxygen, nor inhibitors of myeloperoxidase, had any effect on the cytotoxic activity of normal monocytes. Together, these results indicate that the cytotoxic activity of human monocytes towards sensitized red cells is not dependent on the generation of reactive oxygen derivatives." @default.
• W2402234900 created "2016-06-24" @default.
• W2402234900 creator A5007589576 @default.
• W2402234900 creator A5030169739 @default.
• W2402234900 creator A5057499349 @default.
• W2402234900 creator A5082317947 @default.
• W2402234900 date "1979-08-01" @default.
• W2402234900 modified "2023-09-27" @default.
• W2402234900 title "Cytotoxic activity of human monocytes towards sensitized red cells is not dependent on the generation of reactive oxygen species" @default.
• W2402234900 cites W1256201618 @default.
• W2402234900 cites W1544551687 @default.
• W2402234900 cites W1940436875 @default.
• W2402234900 cites W1947328903 @default.
• W2402234900 cites W1972936152 @default.
• W2402234900 cites W2017772699 @default.
• W2402234900 cites W2023122744 @default.
• W2402234900 cites W2027944740 @default.
• W2402234900 cites W2047202043 @default.
• W2402234900 cites W2069578064 @default.
• W2402234900 cites W2072520316 @default.
• W2402234900 cites W2080801905 @default.
• W2402234900 cites W2113842973 @default.
• W2402234900 cites W2114482761 @default.
• W2402234900 cites W2114643393 @default.
• W2402234900 cites W2135566159 @default.
• W2402234900 cites W2146742981 @default.
• W2402234900 cites W2147033743 @default.
• W2402234900 cites W2342046504 @default.
• W2402234900 cites W2406212962 @default.
• W2402234900 cites W2414296196 @default.
• W2402234900 cites W2416316200 @default.
• W2402234900 cites W2433512011 @default.
• W2402234900 cites W67495 @default.
• W2402234900 doi "https://doi.org/10.1182/blood.v54.2.407.407" @default.
• W2402234900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/222380" @default.
• W2402234900 hasPublicationYear "1979" @default.
• W2402234900 type Work @default.
• W2402234900 sameAs 2402234900 @default.
• W2402234900 citedByCount "34" @default.
• W2402234900 crossrefType "journal-article" @default.
• W2402234900 hasAuthorship W2402234900A5007589576 @default.
• W2402234900 hasAuthorship W2402234900A5030169739 @default.
• W2402234900 hasAuthorship W2402234900A5057499349 @default.
• W2402234900 hasAuthorship W2402234900A5082317947 @default.
• W2402234900 hasBestOaLocation W24022349001 @default.
• W2402234900 hasConcept C109316439 @default.
• W2402234900 hasConcept C139066938 @default.
• W2402234900 hasConcept C153911025 @default.
• W2402234900 hasConcept C154317977 @default.
• W2402234900 hasConcept C160448771 @default.
• W2402234900 hasConcept C178790620 @default.
• W2402234900 hasConcept C181199279 @default.
• W2402234900 hasConcept C185592680 @default.
• W2402234900 hasConcept C202751555 @default.
• W2402234900 hasConcept C203014093 @default.
• W2402234900 hasConcept C203565725 @default.
• W2402234900 hasConcept C2776778087 @default.
• W2402234900 hasConcept C2776914184 @default.
• W2402234900 hasConcept C2777516457 @default.
• W2402234900 hasConcept C2778175462 @default.
• W2402234900 hasConcept C2780795997 @default.
• W2402234900 hasConcept C2781184567 @default.
• W2402234900 hasConcept C48349386 @default.
• W2402234900 hasConcept C533411734 @default.
• W2402234900 hasConcept C540031477 @default.
• W2402234900 hasConcept C55493867 @default.
• W2402234900 hasConcept C86803240 @default.
• W2402234900 hasConceptScore W2402234900C109316439 @default.
• W2402234900 hasConceptScore W2402234900C139066938 @default.
• W2402234900 hasConceptScore W2402234900C153911025 @default.
• W2402234900 hasConceptScore W2402234900C154317977 @default.
• W2402234900 hasConceptScore W2402234900C160448771 @default.
• W2402234900 hasConceptScore W2402234900C178790620 @default.
• W2402234900 hasConceptScore W2402234900C181199279 @default.
• W2402234900 hasConceptScore W2402234900C185592680 @default.
• W2402234900 hasConceptScore W2402234900C202751555 @default.
• W2402234900 hasConceptScore W2402234900C203014093 @default.
• W2402234900 hasConceptScore W2402234900C203565725 @default.
• W2402234900 hasConceptScore W2402234900C2776778087 @default.
• W2402234900 hasConceptScore W2402234900C2776914184 @default.
• W2402234900 hasConceptScore W2402234900C2777516457 @default.
• W2402234900 hasConceptScore W2402234900C2778175462 @default.
• W2402234900 hasConceptScore W2402234900C2780795997 @default.
• W2402234900 hasConceptScore W2402234900C2781184567 @default.
• W2402234900 hasConceptScore W2402234900C48349386 @default.
• W2402234900 hasConceptScore W2402234900C533411734 @default.
• W2402234900 hasConceptScore W2402234900C540031477 @default.
• W2402234900 hasConceptScore W2402234900C55493867 @default.
• W2402234900 hasConceptScore W2402234900C86803240 @default.
• W2402234900 hasIssue "2" @default.
• W2402234900 hasLocation W24022349001 @default.
• W2402234900 hasOpenAccess W2402234900 @default.
• W2402234900 hasPrimaryLocation W24022349001 @default.
• W2402234900 hasRelatedWork W1493143826 @default.
• W2402234900 hasRelatedWork W1543929787 @default.
• W2402234900 hasRelatedWork W1544551687 @default.
• W2402234900 hasRelatedWork W1983084759 @default.
• W2402234900 hasRelatedWork W1984271271 @default.

• next