FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2402708036> ?p ?o ?g. }

• W2402708036 endingPage "37535" @default.
• W2402708036 startingPage "37524" @default.
• W2402708036 abstract "Chemoresistance and epithelial-mesenchymal transition (EMT) in cancer are linked phenomena. EMT contributes to chemoresistance, however, little is known about whether chemotherapy can induce EMT in cancer cells. Here, we found that miR-101 expression was downregulated in cisplatin-resistant non-small cell lung cancer (NSCLC) cells. Restoration of miR-101 expression inhibited EMT and increased the sensitivity of cisplatin-resistant NSCLC cells to cisplatin in vitro by targeting ROCK2. Furthermore, ROCK2 protein level was inversely correlated with miR-101 level in NSCLC tissue samples. Kaplan-Meier analysis revealed that low miR-101 expression in NSCLC was correlated with poor survival time. In summary, our results provide novel mechanistic insights into the role of miR-101/ROCK2 signaling in the cisplatin resistance of NSCLC cells. Targeting of miR-101 is a potential therapeutic approach for NSCLC." @default.
• W2402708036 created "2016-06-24" @default.
• W2402708036 creator A5001312131 @default.
• W2402708036 creator A5003620433 @default.
• W2402708036 creator A5026635242 @default.
• W2402708036 creator A5028303506 @default.
• W2402708036 creator A5060911389 @default.
• W2402708036 creator A5067356990 @default.
• W2402708036 creator A5069973858 @default.
• W2402708036 date "2016-01-09" @default.
• W2402708036 modified "2023-09-25" @default.
• W2402708036 title "Downregulation of miR-101 contributes to epithelial-mesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2" @default.
• W2402708036 cites W1515008413 @default.
• W2402708036 cites W1515566746 @default.
• W2402708036 cites W1558158633 @default.
• W2402708036 cites W1831977902 @default.
• W2402708036 cites W1915692470 @default.
• W2402708036 cites W1964081206 @default.
• W2402708036 cites W1971658408 @default.
• W2402708036 cites W1980422148 @default.
• W2402708036 cites W2013552805 @default.
• W2402708036 cites W2014474987 @default.
• W2402708036 cites W2014691022 @default.
• W2402708036 cites W2015284016 @default.
• W2402708036 cites W2016360721 @default.
• W2402708036 cites W2023024480 @default.
• W2402708036 cites W2023620453 @default.
• W2402708036 cites W2040182688 @default.
• W2402708036 cites W2048373925 @default.
• W2402708036 cites W2049850006 @default.
• W2402708036 cites W2062069198 @default.
• W2402708036 cites W2077603983 @default.
• W2402708036 cites W2104546896 @default.
• W2402708036 cites W2104584000 @default.
• W2402708036 cites W2110146698 @default.
• W2402708036 cites W2121291985 @default.
• W2402708036 cites W2149702876 @default.
• W2402708036 cites W2151832198 @default.
• W2402708036 cites W2160609627 @default.
• W2402708036 cites W2161191622 @default.
• W2402708036 cites W2165200432 @default.
• W2402708036 cites W2170552969 @default.
• W2402708036 doi "https://doi.org/10.18632/oncotarget.6852" @default.
• W2402708036 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5122329" @default.
• W2402708036 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27229528" @default.
• W2402708036 hasPublicationYear "2016" @default.
• W2402708036 type Work @default.
• W2402708036 sameAs 2402708036 @default.
• W2402708036 citedByCount "47" @default.
• W2402708036 countsByYear W24027080362016 @default.
• W2402708036 countsByYear W24027080362017 @default.
• W2402708036 countsByYear W24027080362018 @default.
• W2402708036 countsByYear W24027080362019 @default.
• W2402708036 countsByYear W24027080362020 @default.
• W2402708036 countsByYear W24027080362021 @default.
• W2402708036 countsByYear W24027080362022 @default.
• W2402708036 countsByYear W24027080362023 @default.
• W2402708036 crossrefType "journal-article" @default.
• W2402708036 hasAuthorship W2402708036A5001312131 @default.
• W2402708036 hasAuthorship W2402708036A5003620433 @default.
• W2402708036 hasAuthorship W2402708036A5026635242 @default.
• W2402708036 hasAuthorship W2402708036A5028303506 @default.
• W2402708036 hasAuthorship W2402708036A5060911389 @default.
• W2402708036 hasAuthorship W2402708036A5067356990 @default.
• W2402708036 hasAuthorship W2402708036A5069973858 @default.
• W2402708036 hasBestOaLocation W24027080361 @default.
• W2402708036 hasConcept C104317684 @default.
• W2402708036 hasConcept C121608353 @default.
• W2402708036 hasConcept C126322002 @default.
• W2402708036 hasConcept C127561419 @default.
• W2402708036 hasConcept C142724271 @default.
• W2402708036 hasConcept C143998085 @default.
• W2402708036 hasConcept C198826908 @default.
• W2402708036 hasConcept C2776256026 @default.
• W2402708036 hasConcept C2776694085 @default.
• W2402708036 hasConcept C2777093181 @default.
• W2402708036 hasConcept C2778239845 @default.
• W2402708036 hasConcept C2779013556 @default.
• W2402708036 hasConcept C2779331819 @default.
• W2402708036 hasConcept C502942594 @default.
• W2402708036 hasConcept C55493867 @default.
• W2402708036 hasConcept C62478195 @default.
• W2402708036 hasConcept C71924100 @default.
• W2402708036 hasConcept C76419328 @default.
• W2402708036 hasConcept C86803240 @default.
• W2402708036 hasConcept C95444343 @default.
• W2402708036 hasConceptScore W2402708036C104317684 @default.
• W2402708036 hasConceptScore W2402708036C121608353 @default.
• W2402708036 hasConceptScore W2402708036C126322002 @default.
• W2402708036 hasConceptScore W2402708036C127561419 @default.
• W2402708036 hasConceptScore W2402708036C142724271 @default.
• W2402708036 hasConceptScore W2402708036C143998085 @default.
• W2402708036 hasConceptScore W2402708036C198826908 @default.
• W2402708036 hasConceptScore W2402708036C2776256026 @default.
• W2402708036 hasConceptScore W2402708036C2776694085 @default.
• W2402708036 hasConceptScore W2402708036C2777093181 @default.
• W2402708036 hasConceptScore W2402708036C2778239845 @default.
• W2402708036 hasConceptScore W2402708036C2779013556 @default.

• next