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- W2402711909 abstract "The influence of cellular differentiation and CEA-production by colorectal tumor cells on experimental hepatic metastases was studied. Eight human colon cancer cell lines were injected into the spleen of athymic mice. The four poorly differentiated, non or low CEA producing cell lines were poorly metastatic to the liver. In contrast, the four well-differentiated cell lines which produce moderate to high levels of CEA were highly metastatic. We conclude in this animal model that poorly differentiated, non or low CEA producing colorectal cell lines have a lower metastatic potential compared to the well-differentiated, high CEA producing tumor cells." @default.
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- W2402711909 date "1992-03-01" @default.
- W2402711909 modified "2023-09-23" @default.
- W2402711909 title "[Experimental liver metastases of human colonic cancer: correlation with degree of differentiation and CEA production]." @default.
- W2402711909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1592651" @default.
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