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- W2402715013 abstract "1 A hypothesis in characterizing human depression is that change in the brain‟s basal ganglia results in a decline of motor coordination [6][8][14]. Such a neuro-physiological change may therefore affect laryngeal control and dynamics. Under this hypothesis, toward the goal of objective monitoring of depression severity, we investigate vocal-source biomarkers for depression; specifically, source features that may relate to precision in motor control, including vocal-fold shimmer and jitter, degree of aspiration, fundamental frequency dynamics, and frequency-dependence of variability and velocity of energy. We use a 35-subject database collected by Mundt et al. [1] in which subjects were treated over a six-week period, and investigate correlation of our features with clinical (HAMD), as well as self-reported (QIDS) Total subject assessment scores. To explicitly address the motor aspect of depression, we compute correlations with the Psychomotor Retardation component of clinical and self-reported Total assessments. For our longitudinal database, most correlations point to statistical relationships of our vocal-source biomarkers with psychomotor activity, as well as with depression severity." @default.
- W2402715013 created "2016-06-24" @default.
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- W2402715013 date "2012-09-09" @default.
- W2402715013 modified "2023-10-17" @default.
- W2402715013 title "Vocal-source biomarkers for depression: a link to psychomotor activity" @default.
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- W2402715013 doi "https://doi.org/10.21437/interspeech.2012-311" @default.
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