Matches in SemOpenAlex for { <https://semopenalex.org/work/W2402804013> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2402804013 endingPage "64" @default.
- W2402804013 startingPage "558" @default.
- W2402804013 abstract "Studies were carried out to test whether tolerance to alloantigens and to heterologous proteins could be induced in (NZB X NZW)F1 (B/W) female mice, compared with females of various other mouse strains, including BALB/c, C3H/eb, C57Bl/Ka and (BALB/c X C57Bl/6)F1. Untreated BALB/c and B/W mice were resistant to tolerance induction by deaggregated BSA, while all other strains were susceptible, as indicated by their lack of response to antigen challenge. Tolerance induction to BSA was further potentiated in all mouse strains including BALB/c with the exception of B/W, following prior conditioning of the mice with total lymphoid irradiation (TLI). Similarly, specific and permanent tolerance to H-2 incompatible alloantigens was successfully induced in TLI conditioned BALB/c, C3H/eb, (BALB/c X C57Bl/6)F1 injected with bone marrow cells, however, B/W mice were resistant. Stable chimeras could be established in TLI treated B/W mice only across a semi-allogeneic combination (BALB/c--greater than B/W). No graft vs host disease (GVHD) was observed in any of the chimeras including B/W mice. We conclude that B/W mice are resistant to tolerance induction to heterologous proteins and alloantigens, even after TLI conditioning. We postulate that this phenomenon is a function of both the intrinsic properties of the haemopoietic stem cells, including their differentiated progeny, as well as characteristics of their cellular microenvironment." @default.
- W2402804013 created "2016-06-24" @default.
- W2402804013 creator A5009519906 @default.
- W2402804013 creator A5027379912 @default.
- W2402804013 creator A5046291426 @default.
- W2402804013 creator A5059915616 @default.
- W2402804013 date "1983-03-01" @default.
- W2402804013 modified "2023-09-23" @default.
- W2402804013 title "Regulation of the immune response in experimental models of autoimmune disorders: resistance of (NZB X NZW)F1 mice to tolerance induction in vivo." @default.
- W2402804013 cites W1487711285 @default.
- W2402804013 cites W1526018962 @default.
- W2402804013 cites W1538723183 @default.
- W2402804013 cites W1547798144 @default.
- W2402804013 cites W1561554425 @default.
- W2402804013 cites W1571615542 @default.
- W2402804013 cites W1602504789 @default.
- W2402804013 cites W1659411660 @default.
- W2402804013 cites W1758704938 @default.
- W2402804013 cites W1910870532 @default.
- W2402804013 cites W1946566853 @default.
- W2402804013 cites W1986009991 @default.
- W2402804013 cites W1997970219 @default.
- W2402804013 cites W2014607136 @default.
- W2402804013 cites W2018865778 @default.
- W2402804013 cites W2073536631 @default.
- W2402804013 cites W2080223016 @default.
- W2402804013 cites W2080883834 @default.
- W2402804013 cites W2093314243 @default.
- W2402804013 cites W2108782166 @default.
- W2402804013 cites W2112122730 @default.
- W2402804013 cites W2152405804 @default.
- W2402804013 cites W2158167763 @default.
- W2402804013 cites W2158669275 @default.
- W2402804013 cites W2169398695 @default.
- W2402804013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1536798" @default.
- W2402804013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6851246" @default.
- W2402804013 hasPublicationYear "1983" @default.
- W2402804013 type Work @default.
- W2402804013 sameAs 2402804013 @default.
- W2402804013 citedByCount "2" @default.
- W2402804013 crossrefType "journal-article" @default.
- W2402804013 hasAuthorship W2402804013A5009519906 @default.
- W2402804013 hasAuthorship W2402804013A5027379912 @default.
- W2402804013 hasAuthorship W2402804013A5046291426 @default.
- W2402804013 hasAuthorship W2402804013A5059915616 @default.
- W2402804013 hasConcept C104317684 @default.
- W2402804013 hasConcept C147483822 @default.
- W2402804013 hasConcept C153911025 @default.
- W2402804013 hasConcept C203014093 @default.
- W2402804013 hasConcept C207001950 @default.
- W2402804013 hasConcept C2777702733 @default.
- W2402804013 hasConcept C2779456560 @default.
- W2402804013 hasConcept C2780007613 @default.
- W2402804013 hasConcept C2780115692 @default.
- W2402804013 hasConcept C54355233 @default.
- W2402804013 hasConcept C86803240 @default.
- W2402804013 hasConcept C8891405 @default.
- W2402804013 hasConceptScore W2402804013C104317684 @default.
- W2402804013 hasConceptScore W2402804013C147483822 @default.
- W2402804013 hasConceptScore W2402804013C153911025 @default.
- W2402804013 hasConceptScore W2402804013C203014093 @default.
- W2402804013 hasConceptScore W2402804013C207001950 @default.
- W2402804013 hasConceptScore W2402804013C2777702733 @default.
- W2402804013 hasConceptScore W2402804013C2779456560 @default.
- W2402804013 hasConceptScore W2402804013C2780007613 @default.
- W2402804013 hasConceptScore W2402804013C2780115692 @default.
- W2402804013 hasConceptScore W2402804013C54355233 @default.
- W2402804013 hasConceptScore W2402804013C86803240 @default.
- W2402804013 hasConceptScore W2402804013C8891405 @default.
- W2402804013 hasIssue "3" @default.
- W2402804013 hasLocation W24028040131 @default.
- W2402804013 hasOpenAccess W2402804013 @default.
- W2402804013 hasPrimaryLocation W24028040131 @default.
- W2402804013 hasRelatedWork W1217682272 @default.
- W2402804013 hasRelatedWork W1769978316 @default.
- W2402804013 hasRelatedWork W1979439339 @default.
- W2402804013 hasRelatedWork W1980792852 @default.
- W2402804013 hasRelatedWork W2002569717 @default.
- W2402804013 hasRelatedWork W2011183043 @default.
- W2402804013 hasRelatedWork W2034707118 @default.
- W2402804013 hasRelatedWork W2049646220 @default.
- W2402804013 hasRelatedWork W2462996121 @default.
- W2402804013 hasRelatedWork W70067030 @default.
- W2402804013 hasVolume "51" @default.
- W2402804013 isParatext "false" @default.
- W2402804013 isRetracted "false" @default.
- W2402804013 magId "2402804013" @default.
- W2402804013 workType "article" @default.