FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2402848232> ?p ?o ?g. }

• W2402848232 endingPage "651" @default.
• W2402848232 startingPage "643" @default.
• W2402848232 abstract "Abstract Background Being small for gestational age ( SGA ), a foetal growth abnormality, has a long‐lasting impact on childhood health. Its aetiology and underlying mechanisms are not well understood. Underlying epigenetic changes of imprinted genes have emerged as a potential pathological pathway because they may be associated with growth, including SGA . As a common methyl donor, folic acid ( FA ) is essential for DNA methylation, synthesis and repair, and FA supplementation is widely recommended for women planning pregnancy. The present study aimed to investigate the inter‐relationships among methylation levels of two imprinted genes [ H19 differentially methylated regions ( DMR s) and MEST DMR s], maternal FA supplementation and SGA . Methods We conducted a case–control study. Umbilical cord blood was taken from 39 SGA infants and 49 controls whose birth weights are appropriate for gestational age ( AGA ). DNA methylation levels of H19 and MEST DMR s were determined by an analysis of mass array quantitative methylation. Results Statistically significantly higher methylation levels were observed at sites 7.8, 9 and 17.18 of H19 ( P = 0.030, 0.016 and 0.050, respectively) in the SGA infants compared to the AGA group. In addition, the association was stronger in male births where the mothers took FA around conception at six H19 sites ( P = 0.004, 0.005, 0.048, 0.002, 0.021 and 0.005, respectively). Conclusions Methylation levels at H19 DMR s were higher in SGA infants compared to AGA controls. It appears that the association may be influenced by maternal peri‐conception FA supplementation and also be sex‐specific." @default.
• W2402848232 created "2016-06-24" @default.
• W2402848232 creator A5011497989 @default.
• W2402848232 creator A5026397154 @default.
• W2402848232 creator A5032130955 @default.
• W2402848232 creator A5041564633 @default.
• W2402848232 creator A5046846544 @default.
• W2402848232 creator A5047077004 @default.
• W2402848232 creator A5052459891 @default.
• W2402848232 creator A5052650664 @default.
• W2402848232 creator A5075201276 @default.
• W2402848232 creator A5085629666 @default.
• W2402848232 creator A5086133674 @default.
• W2402848232 creator A5086522210 @default.
• W2402848232 date "2016-05-27" @default.
• W2402848232 modified "2023-10-15" @default.
• W2402848232 title "Effects of maternal folic acid supplementation on gene methylation and being small for gestational age" @default.
• W2402848232 cites W1590914074 @default.
• W2402848232 cites W1933482556 @default.
• W2402848232 cites W1970138332 @default.
• W2402848232 cites W1970721575 @default.
• W2402848232 cites W1972379625 @default.
• W2402848232 cites W1973047916 @default.
• W2402848232 cites W1974178028 @default.
• W2402848232 cites W1976695083 @default.
• W2402848232 cites W1982427362 @default.
• W2402848232 cites W1996283949 @default.
• W2402848232 cites W1998940020 @default.
• W2402848232 cites W2003211931 @default.
• W2402848232 cites W2004708040 @default.
• W2402848232 cites W2004714113 @default.
• W2402848232 cites W2008982730 @default.
• W2402848232 cites W2009533183 @default.
• W2402848232 cites W2009877633 @default.
• W2402848232 cites W2012568079 @default.
• W2402848232 cites W2013720766 @default.
• W2402848232 cites W2013991501 @default.
• W2402848232 cites W2017472084 @default.
• W2402848232 cites W2026274018 @default.
• W2402848232 cites W2027667548 @default.
• W2402848232 cites W2032788228 @default.
• W2402848232 cites W2042837697 @default.
• W2402848232 cites W2043973819 @default.
• W2402848232 cites W2048002279 @default.
• W2402848232 cites W2048052538 @default.
• W2402848232 cites W2053923110 @default.
• W2402848232 cites W2055876554 @default.
• W2402848232 cites W2059216570 @default.
• W2402848232 cites W2073472080 @default.
• W2402848232 cites W2081064915 @default.
• W2402848232 cites W2087120120 @default.
• W2402848232 cites W2088258048 @default.
• W2402848232 cites W2096113102 @default.
• W2402848232 cites W2096177579 @default.
• W2402848232 cites W2096542132 @default.
• W2402848232 cites W2100491520 @default.
• W2402848232 cites W2103421101 @default.
• W2402848232 cites W2104476055 @default.
• W2402848232 cites W2106557257 @default.
• W2402848232 cites W2106681373 @default.
• W2402848232 cites W2106926581 @default.
• W2402848232 cites W2116772407 @default.
• W2402848232 cites W2118964420 @default.
• W2402848232 cites W2120731490 @default.
• W2402848232 cites W2122516533 @default.
• W2402848232 cites W2125095396 @default.
• W2402848232 cites W2125620273 @default.
• W2402848232 cites W2130673076 @default.
• W2402848232 cites W2141144827 @default.
• W2402848232 cites W2141737525 @default.
• W2402848232 cites W2146675117 @default.
• W2402848232 cites W2153491127 @default.
• W2402848232 cites W2155196041 @default.
• W2402848232 cites W2155886698 @default.
• W2402848232 cites W2157577918 @default.
• W2402848232 cites W2158060077 @default.
• W2402848232 cites W2158384762 @default.
• W2402848232 cites W2168206205 @default.
• W2402848232 cites W2169549058 @default.
• W2402848232 cites W2171314923 @default.
• W2402848232 cites W4290960820 @default.
• W2402848232 doi "https://doi.org/10.1111/jhn.12369" @default.
• W2402848232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27230729" @default.
• W2402848232 hasPublicationYear "2016" @default.
• W2402848232 type Work @default.
• W2402848232 sameAs 2402848232 @default.
• W2402848232 citedByCount "24" @default.
• W2402848232 countsByYear W24028482322017 @default.
• W2402848232 countsByYear W24028482322018 @default.
• W2402848232 countsByYear W24028482322019 @default.
• W2402848232 countsByYear W24028482322020 @default.
• W2402848232 countsByYear W24028482322021 @default.
• W2402848232 countsByYear W24028482322022 @default.
• W2402848232 countsByYear W24028482322023 @default.
• W2402848232 crossrefType "journal-article" @default.
• W2402848232 hasAuthorship W2402848232A5011497989 @default.
• W2402848232 hasAuthorship W2402848232A5026397154 @default.
• W2402848232 hasAuthorship W2402848232A5032130955 @default.

• next