FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2403166611> ?p ?o ?g. }

• W2403166611 endingPage "51" @default.
• W2403166611 startingPage "341" @default.
• W2403166611 abstract "The study of T-cell subpopulation: T CD3+, T CD4+, T CD8+; NK CD16+ and B CD19+ cells as well as of serum concentrations of immunoglobulins G, A, M, E, complement components C3c and C4, total circulating immune complexes (CIC), CRP, haptoglobin, ceruloplasmin and transferin, was carried out in 16 males, smokers and non-smokers. The control group of smokers and non-smokers comprised 36 males not exposed to any chemical compound. The study was performed also in two groups of non-smokers: 5 workers occupationally exposed and 7 non-exposed controls. For the determination of T-cells, NK- and B CD19+ cells populations monoclonal antibodies were used in indirect immunofluorescence tests. Passive sampling spectrophotometric method was employed to determine NO2 and NO concentrations in the work environment air. Their mean values were 0.0867 +/- 0,0585 mg x m-3 (from 0.0165 to 0.1960) and 0.0614 +/- 0.0263 mg x m-3 (from 0.0220 to 0.1090), respectively. The number of total leucocytes and lymphocytes in the group of 16 smokers and non-smokers exposed to NO2 and NO was increased. Stimulation T-cells line in the men exposed to NO2 and NO was evidenced by an increased number of T CD3+ cells, about two-fold increase in absolute number of T CD4+ cells (p < 0.001), an increased number of T CD8+ cells (p < 0.001) and by an enhanced value (by 24.7%) of the T CD4+/T CD8+ ratio. In the group of 16 persons exposed to NO2 and NO serum IgG concentration was elevated (p < 0.01), C3c C4 decreased (p < 0.001), and serum CIC enhanced by about two times (p < 0.001). Stimulation T-cells line in the groups of 5 non-smoking workers exposed to NO2 and NO was evidenced by an increased number of T CD3+ (p < 0.05), T CD4+ (p < 0.05) and T CD8+ cells but without any change in the value of the T CD4+/T CD8+ ratio. In addition, decreased serum C3c and C4 levels together with serum CIC elevated by 76.7% (p < 0.05) were evidenced in this group on non-smokers. Moreover, significant positive correlations between NO2 concentrations in the air and the numbers of total lymphocytes, T CD3+, TCD4+, T CD8+ cells or IgG: (magnitude of r in the range between 0.31 and 0.71), as well as significant negative correlations between NO2 concentrations in the air and C3c (r = 0.44) in the group of 16 smoking and non-smoking workers were calculated. In this group significant positive correlation between NO concentrations in the air of the workplace and counts of T CD3+, T CD8+, B CD19+ (magnitude of r in the range between 0.51 and 0.63), haptoglobin and ceruloplasmin (magnitude of r from 0.37 to 0.58), as well as significant negative correlation between NO concentrations in the air and serum levels of IgG, IgA and IgM (magnitude of r from -0.67 to -0.47) and CIC (magnitude of r = -0.39) were also observed. In the group of 5 exposed non-smoking workers, the values of correlation coefficients magnitude of r between NO2 and NO concentrations in the work environment air and immunological parameters were similar to those in the whole group. The results obtained suggest that during occupational exposure NO2 may play a more important role mainly in the process of inflammation but exogenous NO seems to act as modulating factor of this proinflammatory NO2 effect through a greater and exposure-dependent influence mainly on B CD19+ cells and other parameters of humoral immunity." @default.
• W2403166611 created "2016-06-24" @default.
• W2403166611 creator A5012403043 @default.
• W2403166611 creator A5048076001 @default.
• W2403166611 creator A5059873678 @default.
• W2403166611 creator A5085467930 @default.
• W2403166611 creator A5087715374 @default.
• W2403166611 date "1998-01-01" @default.
• W2403166611 modified "2023-10-18" @default.
• W2403166611 title "[The effects of occupational exposure to nitrogen dioxide (NO2) on the immunological parameters in workers]." @default.
• W2403166611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9816580" @default.
• W2403166611 hasPublicationYear "1998" @default.
• W2403166611 type Work @default.
• W2403166611 sameAs 2403166611 @default.
• W2403166611 citedByCount "2" @default.
• W2403166611 countsByYear W24031666112016 @default.
• W2403166611 crossrefType "journal-article" @default.
• W2403166611 hasAuthorship W2403166611A5012403043 @default.
• W2403166611 hasAuthorship W2403166611A5048076001 @default.
• W2403166611 hasAuthorship W2403166611A5059873678 @default.
• W2403166611 hasAuthorship W2403166611A5085467930 @default.
• W2403166611 hasAuthorship W2403166611A5087715374 @default.
• W2403166611 hasConcept C114684123 @default.
• W2403166611 hasConcept C126322002 @default.
• W2403166611 hasConcept C134018914 @default.
• W2403166611 hasConcept C16685009 @default.
• W2403166611 hasConcept C167672396 @default.
• W2403166611 hasConcept C185592680 @default.
• W2403166611 hasConcept C203014093 @default.
• W2403166611 hasConcept C206396517 @default.
• W2403166611 hasConcept C2778957590 @default.
• W2403166611 hasConcept C28452662 @default.
• W2403166611 hasConcept C71924100 @default.
• W2403166611 hasConcept C8891405 @default.
• W2403166611 hasConceptScore W2403166611C114684123 @default.
• W2403166611 hasConceptScore W2403166611C126322002 @default.
• W2403166611 hasConceptScore W2403166611C134018914 @default.
• W2403166611 hasConceptScore W2403166611C16685009 @default.
• W2403166611 hasConceptScore W2403166611C167672396 @default.
• W2403166611 hasConceptScore W2403166611C185592680 @default.
• W2403166611 hasConceptScore W2403166611C203014093 @default.
• W2403166611 hasConceptScore W2403166611C206396517 @default.
• W2403166611 hasConceptScore W2403166611C2778957590 @default.
• W2403166611 hasConceptScore W2403166611C28452662 @default.
• W2403166611 hasConceptScore W2403166611C71924100 @default.
• W2403166611 hasConceptScore W2403166611C8891405 @default.
• W2403166611 hasIssue "4" @default.
• W2403166611 hasLocation W24031666111 @default.
• W2403166611 hasOpenAccess W2403166611 @default.
• W2403166611 hasPrimaryLocation W24031666111 @default.
• W2403166611 hasRelatedWork W1981184132 @default.
• W2403166611 hasRelatedWork W2031128886 @default.
• W2403166611 hasRelatedWork W2034160312 @default.
• W2403166611 hasRelatedWork W2083749292 @default.
• W2403166611 hasRelatedWork W2379993320 @default.
• W2403166611 hasRelatedWork W2386984432 @default.
• W2403166611 hasRelatedWork W2403166611 @default.
• W2403166611 hasRelatedWork W2423374434 @default.
• W2403166611 hasRelatedWork W3031903147 @default.
• W2403166611 hasRelatedWork W3032205898 @default.
• W2403166611 hasVolume "49" @default.
• W2403166611 isParatext "false" @default.
• W2403166611 isRetracted "false" @default.
• W2403166611 magId "2403166611" @default.
• W2403166611 workType "article" @default.