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- W2403659480 abstract "Granulomatous interstitial nephritis has been observed in <1% of native renal biopsies. Here, we describe two patients with granulomatous interstitial nephritis in relation to Crohn's disease. Circulating helper and cytotoxic T cells were highly activated, and both cell types predominated in the interstitial infiltrate, indicating a cellular autoimmune response. After immunosuppressive treatment, renal function either improved or stabilized in both patients. In conclusion, granulomatous interstitial nephritis is a genuine extraintestinal manifestation of Crohn's disease, the treatment of which should include immunosuppressive agents." @default.
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- W2403659480 date "2016-05-26" @default.
- W2403659480 modified "2023-10-05" @default.
- W2403659480 title "Granulomatous interstitial nephritis and Crohn's disease" @default.
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- W2403659480 doi "https://doi.org/10.1093/ckj/sfw041" @default.
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