Matches in SemOpenAlex for { <https://semopenalex.org/work/W2403669698> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2403669698 endingPage "27" @default.
- W2403669698 startingPage "1317" @default.
- W2403669698 abstract "Mild to moderate hypertension still remains poorly controlled. This relates to multiple factors including low antihypertensive efficacy of single drug therapies, reluctance of primary care physicians to modify or titrate initially chosen therapy to obtain target blood pressure and poor compliance with medication. Evidence discussed in the present paper points to superior control of blood pressure by combinations of low doses of two drugs compared with monotherapy in regular doses. This superior effectiveness of combined therapy relates to a better antihypertensive efficacy and higher response rates in the low range of doses as the result of complementary mechanisms of antihypertensive effects. It is associated with better tolerance as the result of a lower rate of side effects in the low range of dosing, improved compliance from better tolerance and simple drug regimen, and lower cost. Increased use of fixed, low dose combination therapies can be expected to result in better control of arterial hypertension in the population. Given the evidence for superior antihypertensive efficacy and better tolerability, and the absence of harm from fixed, low dose drug combinations per se, this alternative deserves more consideration in the guidelines of major hypertension organizations." @default.
- W2403669698 created "2016-06-24" @default.
- W2403669698 creator A5035274018 @default.
- W2403669698 creator A5079463826 @default.
- W2403669698 date "2002-12-01" @default.
- W2403669698 modified "2023-09-25" @default.
- W2403669698 title "Combination therapy as first-line treatment of arterial hypertension." @default.
- W2403669698 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12518184" @default.
- W2403669698 hasPublicationYear "2002" @default.
- W2403669698 type Work @default.
- W2403669698 sameAs 2403669698 @default.
- W2403669698 citedByCount "7" @default.
- W2403669698 countsByYear W24036696982022 @default.
- W2403669698 crossrefType "journal-article" @default.
- W2403669698 hasAuthorship W2403669698A5035274018 @default.
- W2403669698 hasAuthorship W2403669698A5079463826 @default.
- W2403669698 hasConcept C126322002 @default.
- W2403669698 hasConcept C15744967 @default.
- W2403669698 hasConcept C164705383 @default.
- W2403669698 hasConcept C177713679 @default.
- W2403669698 hasConcept C197934379 @default.
- W2403669698 hasConcept C2776999253 @default.
- W2403669698 hasConcept C2777288759 @default.
- W2403669698 hasConcept C2778375690 @default.
- W2403669698 hasConcept C2780035454 @default.
- W2403669698 hasConcept C2781413609 @default.
- W2403669698 hasConcept C2781460075 @default.
- W2403669698 hasConcept C2908647359 @default.
- W2403669698 hasConcept C500440147 @default.
- W2403669698 hasConcept C71924100 @default.
- W2403669698 hasConcept C77805123 @default.
- W2403669698 hasConcept C84393581 @default.
- W2403669698 hasConcept C98274493 @default.
- W2403669698 hasConcept C99454951 @default.
- W2403669698 hasConceptScore W2403669698C126322002 @default.
- W2403669698 hasConceptScore W2403669698C15744967 @default.
- W2403669698 hasConceptScore W2403669698C164705383 @default.
- W2403669698 hasConceptScore W2403669698C177713679 @default.
- W2403669698 hasConceptScore W2403669698C197934379 @default.
- W2403669698 hasConceptScore W2403669698C2776999253 @default.
- W2403669698 hasConceptScore W2403669698C2777288759 @default.
- W2403669698 hasConceptScore W2403669698C2778375690 @default.
- W2403669698 hasConceptScore W2403669698C2780035454 @default.
- W2403669698 hasConceptScore W2403669698C2781413609 @default.
- W2403669698 hasConceptScore W2403669698C2781460075 @default.
- W2403669698 hasConceptScore W2403669698C2908647359 @default.
- W2403669698 hasConceptScore W2403669698C500440147 @default.
- W2403669698 hasConceptScore W2403669698C71924100 @default.
- W2403669698 hasConceptScore W2403669698C77805123 @default.
- W2403669698 hasConceptScore W2403669698C84393581 @default.
- W2403669698 hasConceptScore W2403669698C98274493 @default.
- W2403669698 hasConceptScore W2403669698C99454951 @default.
- W2403669698 hasIssue "12" @default.
- W2403669698 hasLocation W24036696981 @default.
- W2403669698 hasOpenAccess W2403669698 @default.
- W2403669698 hasPrimaryLocation W24036696981 @default.
- W2403669698 hasRelatedWork W1784252295 @default.
- W2403669698 hasRelatedWork W1964475156 @default.
- W2403669698 hasRelatedWork W1983892688 @default.
- W2403669698 hasRelatedWork W2011373688 @default.
- W2403669698 hasRelatedWork W2047134357 @default.
- W2403669698 hasRelatedWork W2067385260 @default.
- W2403669698 hasRelatedWork W2100002639 @default.
- W2403669698 hasRelatedWork W2350948938 @default.
- W2403669698 hasRelatedWork W2395724646 @default.
- W2403669698 hasRelatedWork W2793659366 @default.
- W2403669698 hasVolume "18" @default.
- W2403669698 isParatext "false" @default.
- W2403669698 isRetracted "false" @default.
- W2403669698 magId "2403669698" @default.
- W2403669698 workType "article" @default.