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- W2403944660 abstract "地塞米松（dexamethasone）是人工合成的肾上腺皮质激素,由于其显著的药理作用和廉价易获得的特性成为众多学者研究的热点.故广泛应用于各科治疗多种疾病,是临床常用药物.一氧化氮（nitric oxide,NO）及诱导型一氧化氮台酶（inducible nitric oxide synthase,iNOS）是体内半衰期极短的体液因子,其生物效应广泛.近几年的研究结果表明,NO及iNOS与缺血再灌注损伤关系密切,参与缺血再灌注损伤的发生、发展、预后等多个过程,成为缺血再灌注损伤预处理一个非常重要的研究领域.肝脏缺血再灌注损伤（hepatic ischemia-reperfu-sionin jury,HIRI）是由于需要阻断肝门的肝脏手术、肝脏移植,失血性休克以及晚期脓毒血症等各种原因导致肝血流中断或不足使肝脏缺血,当恢复血供再灌注后,肝细胞功能代谢障碍及结构破坏反而加重,器官功能进一步恶化的现象。" @default.
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- W2403944660 date "2010-11-01" @default.
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- W2403944660 title "[Use of dexamethasone in liver ischemia-reperfusion injury]." @default.
- W2403944660 doi "https://doi.org/10.3760/cma.j.issn.1007-3418.2010.11.027" @default.
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