FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2404222912> ?p ?o ?g. }

• W2404222912 endingPage "805" @default.
• W2404222912 startingPage "797" @default.
• W2404222912 abstract "Ubiquinol-cytochrome c reductase hinge protein (UQCRH), as a connecter between cytochrome c1 with cytochrome c in complex III of respiratory chain, is top-ranked hypermethylated gene in clear cell renal cell carcinoma (ccRCC). This study aims to evaluate the impact of UQCRH on recurrence and survival of 424 ccRCC patients enrolled retrospectively from a single institution after surgical resection using immunohistochemistry method. UQCRH was specifically downregulated in ccRCC, compared with papillary and chromophobe RCC. Moreover, patients with low UQCRH were prone to possess high T stage and TNM stage and associated with poor survival and early recurrence. UQCRH remained an independent favorable prognosticator for OS (Hazard rate [HR]: 0.510, 95% CI: 0.328-0.795, p=0.003) and RFS (HR: 0.506, 95% CI: 0.334-0.767, p=0.001) adjusting with other well-established factors using backward Cox model. Furthermore, in stratified subgroups, patients with low UQCRH had an increased risk of recurrence (HR: 0.452, 95% CI: 0.261-0.783, p=0.005) and mortality (HR: 0.386, 95% CI: 0.205-0.726, p=0.003) in subgroup of early TNM stage. Taken together, UQCRH is a potential independent favorable prognostic factor for recurrence and survival of patients with ccRCC after nephrectomy." @default.
• W2404222912 created "2016-06-24" @default.
• W2404222912 creator A5014477100 @default.
• W2404222912 creator A5034409741 @default.
• W2404222912 creator A5034840502 @default.
• W2404222912 creator A5037539383 @default.
• W2404222912 creator A5046719955 @default.
• W2404222912 creator A5074670112 @default.
• W2404222912 creator A5083553088 @default.
• W2404222912 date "2016-01-01" @default.
• W2404222912 modified "2023-09-27" @default.
• W2404222912 title "Prognostic significance of ubiquinol-cytochrome c reductase hinge protein expression in patients with clear cell renal cell carcinoma." @default.
• W2404222912 cites W1638874881 @default.
• W2404222912 cites W1966485211 @default.
• W2404222912 cites W1967727543 @default.
• W2404222912 cites W2019357766 @default.
• W2404222912 cites W2020498032 @default.
• W2404222912 cites W2021793290 @default.
• W2404222912 cites W2029436635 @default.
• W2404222912 cites W2031027126 @default.
• W2404222912 cites W2039734446 @default.
• W2404222912 cites W2054987125 @default.
• W2404222912 cites W2056688967 @default.
• W2404222912 cites W2069672800 @default.
• W2404222912 cites W2073390825 @default.
• W2404222912 cites W2082394458 @default.
• W2404222912 cites W2086756221 @default.
• W2404222912 cites W2101146511 @default.
• W2404222912 cites W2119113195 @default.
• W2404222912 cites W2147031820 @default.
• W2404222912 cites W2161740846 @default.
• W2404222912 cites W2335012284 @default.
• W2404222912 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4859884" @default.
• W2404222912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27186431" @default.
• W2404222912 hasPublicationYear "2016" @default.
• W2404222912 type Work @default.
• W2404222912 sameAs 2404222912 @default.
• W2404222912 citedByCount "3" @default.
• W2404222912 countsByYear W24042229122016 @default.
• W2404222912 countsByYear W24042229122021 @default.
• W2404222912 countsByYear W24042229122022 @default.
• W2404222912 crossrefType "journal-article" @default.
• W2404222912 hasAuthorship W2404222912A5014477100 @default.
• W2404222912 hasAuthorship W2404222912A5034409741 @default.
• W2404222912 hasAuthorship W2404222912A5034840502 @default.
• W2404222912 hasAuthorship W2404222912A5037539383 @default.
• W2404222912 hasAuthorship W2404222912A5046719955 @default.
• W2404222912 hasAuthorship W2404222912A5074670112 @default.
• W2404222912 hasAuthorship W2404222912A5083553088 @default.
• W2404222912 hasConcept C126322002 @default.
• W2404222912 hasConcept C143998085 @default.
• W2404222912 hasConcept C146357865 @default.
• W2404222912 hasConcept C151730666 @default.
• W2404222912 hasConcept C207103383 @default.
• W2404222912 hasConcept C2777472916 @default.
• W2404222912 hasConcept C2778560582 @default.
• W2404222912 hasConcept C2780091579 @default.
• W2404222912 hasConcept C2780227381 @default.
• W2404222912 hasConcept C2781278892 @default.
• W2404222912 hasConcept C44249647 @default.
• W2404222912 hasConcept C50382708 @default.
• W2404222912 hasConcept C71924100 @default.
• W2404222912 hasConcept C78795084 @default.
• W2404222912 hasConcept C86803240 @default.
• W2404222912 hasConcept C90924648 @default.
• W2404222912 hasConceptScore W2404222912C126322002 @default.
• W2404222912 hasConceptScore W2404222912C143998085 @default.
• W2404222912 hasConceptScore W2404222912C146357865 @default.
• W2404222912 hasConceptScore W2404222912C151730666 @default.
• W2404222912 hasConceptScore W2404222912C207103383 @default.
• W2404222912 hasConceptScore W2404222912C2777472916 @default.
• W2404222912 hasConceptScore W2404222912C2778560582 @default.
• W2404222912 hasConceptScore W2404222912C2780091579 @default.
• W2404222912 hasConceptScore W2404222912C2780227381 @default.
• W2404222912 hasConceptScore W2404222912C2781278892 @default.
• W2404222912 hasConceptScore W2404222912C44249647 @default.
• W2404222912 hasConceptScore W2404222912C50382708 @default.
• W2404222912 hasConceptScore W2404222912C71924100 @default.
• W2404222912 hasConceptScore W2404222912C78795084 @default.
• W2404222912 hasConceptScore W2404222912C86803240 @default.
• W2404222912 hasConceptScore W2404222912C90924648 @default.
• W2404222912 hasIssue "4" @default.
• W2404222912 hasLocation W24042229121 @default.
• W2404222912 hasOpenAccess W2404222912 @default.
• W2404222912 hasPrimaryLocation W24042229121 @default.
• W2404222912 hasRelatedWork W1509042831 @default.
• W2404222912 hasRelatedWork W1997733825 @default.
• W2404222912 hasRelatedWork W2024184727 @default.
• W2404222912 hasRelatedWork W2030817300 @default.
• W2404222912 hasRelatedWork W2047131672 @default.
• W2404222912 hasRelatedWork W2091967903 @default.
• W2404222912 hasRelatedWork W2168512231 @default.
• W2404222912 hasRelatedWork W2290108094 @default.
• W2404222912 hasRelatedWork W2590280336 @default.
• W2404222912 hasRelatedWork W3094602543 @default.
• W2404222912 hasVolume "6" @default.
• W2404222912 isParatext "false" @default.
• W2404222912 isRetracted "false" @default.

• next