Matches in SemOpenAlex for { <https://semopenalex.org/work/W2404233617> ?p ?o ?g. }
- W2404233617 endingPage "168" @default.
- W2404233617 startingPage "159" @default.
- W2404233617 abstract "Mitochondria are essential for cell growth and survival of most fungal pathogens. Energy (ATP) produced during oxidation/reduction reactions of the electron transport chain (ETC) Complexes I, III and IV (CI, CIII, CIV) fuel cell synthesis. The mitochondria of fungal pathogens are understudied even though more recent published data suggest critical functional assignments to fungal-specific proteins. Proteins of mammalian mitochondria are grouped into 16 functional categories. In this review, we focus upon 11 proteins from 5 of these categories in fungal pathogens, OXPHOS, protein import, stress response, carbon source metabolism, and fission/fusion morphology. As these proteins also are fungal-specific, we hypothesize that they may be exploited as targets in antifungal drug discovery. We also discuss published transcriptional profiling data of mitochondrial CI subunit protein mutants, in which we advance a novel concept those CI subunit proteins have both shared as well as specific responsibilities for providing ATP to cell processes." @default.
- W2404233617 created "2016-06-24" @default.
- W2404233617 creator A5006565021 @default.
- W2404233617 creator A5062665642 @default.
- W2404233617 date "2016-05-18" @default.
- W2404233617 modified "2023-10-17" @default.
- W2404233617 title "Exploiting mitochondria as targets for the development of new antifungals" @default.
- W2404233617 cites W1632467620 @default.
- W2404233617 cites W1913932992 @default.
- W2404233617 cites W1918199612 @default.
- W2404233617 cites W1943133705 @default.
- W2404233617 cites W1964627253 @default.
- W2404233617 cites W1987354838 @default.
- W2404233617 cites W1991149284 @default.
- W2404233617 cites W2003121466 @default.
- W2404233617 cites W2015653219 @default.
- W2404233617 cites W2017438116 @default.
- W2404233617 cites W2032158341 @default.
- W2404233617 cites W2032564765 @default.
- W2404233617 cites W2039859739 @default.
- W2404233617 cites W2042125334 @default.
- W2404233617 cites W2042798497 @default.
- W2404233617 cites W2043717389 @default.
- W2404233617 cites W2059625789 @default.
- W2404233617 cites W2059803549 @default.
- W2404233617 cites W2061851426 @default.
- W2404233617 cites W2062983075 @default.
- W2404233617 cites W2064457538 @default.
- W2404233617 cites W2082150533 @default.
- W2404233617 cites W2089758228 @default.
- W2404233617 cites W2096468377 @default.
- W2404233617 cites W2104259060 @default.
- W2404233617 cites W2107794472 @default.
- W2404233617 cites W2113427739 @default.
- W2404233617 cites W2118725775 @default.
- W2404233617 cites W2119391289 @default.
- W2404233617 cites W2135399192 @default.
- W2404233617 cites W2136145101 @default.
- W2404233617 cites W2136956922 @default.
- W2404233617 cites W2138727594 @default.
- W2404233617 cites W2140164333 @default.
- W2404233617 cites W2140341871 @default.
- W2404233617 cites W2141563676 @default.
- W2404233617 cites W2142456392 @default.
- W2404233617 cites W2146030068 @default.
- W2404233617 cites W2149402355 @default.
- W2404233617 cites W2154845829 @default.
- W2404233617 cites W2155416658 @default.
- W2404233617 cites W2160059531 @default.
- W2404233617 cites W2161169393 @default.
- W2404233617 cites W2165690142 @default.
- W2404233617 cites W2173418873 @default.
- W2404233617 cites W2184546388 @default.
- W2404233617 cites W2262967276 @default.
- W2404233617 cites W2418526777 @default.
- W2404233617 cites W341279500 @default.
- W2404233617 doi "https://doi.org/10.1080/21505594.2016.1188235" @default.
- W2404233617 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5354164" @default.
- W2404233617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27191707" @default.
- W2404233617 hasPublicationYear "2016" @default.
- W2404233617 type Work @default.
- W2404233617 sameAs 2404233617 @default.
- W2404233617 citedByCount "43" @default.
- W2404233617 countsByYear W24042336172017 @default.
- W2404233617 countsByYear W24042336172018 @default.
- W2404233617 countsByYear W24042336172019 @default.
- W2404233617 countsByYear W24042336172020 @default.
- W2404233617 countsByYear W24042336172021 @default.
- W2404233617 countsByYear W24042336172022 @default.
- W2404233617 countsByYear W24042336172023 @default.
- W2404233617 crossrefType "journal-article" @default.
- W2404233617 hasAuthorship W2404233617A5006565021 @default.
- W2404233617 hasAuthorship W2404233617A5062665642 @default.
- W2404233617 hasBestOaLocation W24042336171 @default.
- W2404233617 hasConcept C104292427 @default.
- W2404233617 hasConcept C104317684 @default.
- W2404233617 hasConcept C112243037 @default.
- W2404233617 hasConcept C143065580 @default.
- W2404233617 hasConcept C1491633281 @default.
- W2404233617 hasConcept C28859421 @default.
- W2404233617 hasConcept C55493867 @default.
- W2404233617 hasConcept C57600042 @default.
- W2404233617 hasConcept C86803240 @default.
- W2404233617 hasConcept C95444343 @default.
- W2404233617 hasConceptScore W2404233617C104292427 @default.
- W2404233617 hasConceptScore W2404233617C104317684 @default.
- W2404233617 hasConceptScore W2404233617C112243037 @default.
- W2404233617 hasConceptScore W2404233617C143065580 @default.
- W2404233617 hasConceptScore W2404233617C1491633281 @default.
- W2404233617 hasConceptScore W2404233617C28859421 @default.
- W2404233617 hasConceptScore W2404233617C55493867 @default.
- W2404233617 hasConceptScore W2404233617C57600042 @default.
- W2404233617 hasConceptScore W2404233617C86803240 @default.
- W2404233617 hasConceptScore W2404233617C95444343 @default.
- W2404233617 hasIssue "2" @default.
- W2404233617 hasLocation W24042336171 @default.
- W2404233617 hasLocation W24042336172 @default.
- W2404233617 hasLocation W24042336173 @default.