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- W2404612610 abstract "Thyroid follicular epithelial cells produce thyroxine (T4) and its physiologically active derivative, 3,3',5-triiodothyronine (T3), hormones that regulate critical developmental and metabolic functions. In order for the thyroid to form hormone precursor, iodide, the defining element in thyroid hormone, must cross both blood-facing and luminal sides of the follicular epithelium. The pathway for uptake from blood is well understood, but the mechanism(s) that enable iodide to cross the luminally facing apical membrane remain obscure. This chapter considers the physiological properties of several molecularly characterized anion transport proteins, all of which potentially contribute to the overall mechanism of apical iodide efflux." @default.
- W2404612610 created "2016-06-24" @default.
- W2404612610 creator A5062168167 @default.
- W2404612610 date "2015-01-01" @default.
- W2404612610 modified "2023-10-14" @default.
- W2404612610 title "Apical Iodide Efflux in Thyroid" @default.
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- W2404612610 doi "https://doi.org/10.1016/bs.vh.2014.12.015" @default.
- W2404612610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25817865" @default.
- W2404612610 hasPublicationYear "2015" @default.
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