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- W2404657809 abstract "All living beings are constituted by molecular entities continuously interacting with each other in the complex patterns through which organic material is created and sustained. From the very small to the very large, such interactions involve three-dimensional objects which fit together by virtue of their complementary shapes. Like the pieces in a jigsaw puzzle, parts of objects fit into holes in other objects as they unite to form wholes, which in turn form the parts that combine to form wholes at increasing levels of granularity. Function follows form, and accurate description of the shapes of such molecular entities entails improved reasoning about their activities in biological systems. However, the dynamic, flexible and multi-granular nature of living material presents several challenges for the notions of shapes and holes, analyses of which have thus far largely focused on the shapes of static objects at the everyday perceptual level of granularity. We focus on two such challenges: describing the shapes of objects that change over time, and extending the definition of holes (and their linings) to one that applies across multiple granularity levels." @default.
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- W2404657809 date "2011-01-01" @default.
- W2404657809 modified "2023-09-27" @default.
- W2404657809 title "Parts and Wholes, Shapes and Holes in Living Beings." @default.
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