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- W2405521796 endingPage "236" @default.
- W2405521796 startingPage "218" @default.
- W2405521796 abstract "Hydroxytyrosol and tyrosol are dietary phenolic compounds present in virgin olive oil and wine. Both compounds are also endogenously synthesized in our body as byproducts of dopamine and tyramine metabolisms, respectively. Over the last decades, research into hydroxytyrosol and tyrosol has experienced an increasing interest due to the role that these compounds may play in the prevention of certain pathologies (e.g. cardiovascular, metabolic, neurodegenerative diseases and cancer). The translation of promising in vitro and in vivo biological effects from preclinical studies to the context of human disease prevention initially depends on whether the dose ingested becomes available at the site of action. In this regard, information regarding the bioavailability and metabolic disposition of hydroxytyrosol and tyrosol is of most importance to evaluate the impact they may have on human health. In this review, we discuss and summarize the state of the art of the scientific evidence regarding the processes of absorption, distribution, metabolism and excretion of both hydroxytyrosol and tyrosol. We also examine the impact of these compounds and their metabolites on biological activity in terms of beneficial health effects. Finally, we evaluate the different analytical approaches that have been developed to measure the plasma and urinary levels of hydroxytyrosol, tyrosol and their metabolites." @default.
- W2405521796 created "2016-06-24" @default.
- W2405521796 creator A5002346096 @default.
- W2405521796 creator A5010113440 @default.
- W2405521796 creator A5013461757 @default.
- W2405521796 creator A5017843656 @default.
- W2405521796 creator A5020006084 @default.
- W2405521796 creator A5033539160 @default.
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- W2405521796 creator A5053016661 @default.
- W2405521796 creator A5055803781 @default.
- W2405521796 creator A5083373223 @default.
- W2405521796 creator A5087857627 @default.
- W2405521796 date "2016-04-02" @default.
- W2405521796 modified "2023-10-18" @default.
- W2405521796 title "Metabolic disposition and biological significance of simple phenols of dietary origin: hydroxytyrosol and tyrosol" @default.
- W2405521796 cites W1502413825 @default.
- W2405521796 cites W1854745677 @default.
- W2405521796 cites W1931836456 @default.
- W2405521796 cites W1943585324 @default.
- W2405521796 cites W1964296974 @default.
- W2405521796 cites W1966435884 @default.
- W2405521796 cites W1970359828 @default.
- W2405521796 cites W1974318174 @default.
- W2405521796 cites W1975910971 @default.
- W2405521796 cites W1976922911 @default.
- W2405521796 cites W1980024104 @default.
- W2405521796 cites W1980757555 @default.
- W2405521796 cites W1981702925 @default.
- W2405521796 cites W1983270946 @default.
- W2405521796 cites W1987068054 @default.
- W2405521796 cites W1990054656 @default.
- W2405521796 cites W1992680104 @default.
- W2405521796 cites W1992962943 @default.
- W2405521796 cites W1995733347 @default.
- W2405521796 cites W1995928877 @default.
- W2405521796 cites W1999637509 @default.
- W2405521796 cites W2001327614 @default.
- W2405521796 cites W2004252404 @default.
- W2405521796 cites W2005406899 @default.
- W2405521796 cites W2005646802 @default.
- W2405521796 cites W2007918875 @default.
- W2405521796 cites W2008302075 @default.
- W2405521796 cites W2010339535 @default.
- W2405521796 cites W2018734229 @default.
- W2405521796 cites W2019283802 @default.
- W2405521796 cites W2020301982 @default.
- W2405521796 cites W2021758424 @default.
- W2405521796 cites W2022228444 @default.
- W2405521796 cites W2023994754 @default.
- W2405521796 cites W2025972178 @default.
- W2405521796 cites W2026701024 @default.
- W2405521796 cites W2027957715 @default.
- W2405521796 cites W2028582213 @default.
- W2405521796 cites W2030119339 @default.
- W2405521796 cites W2030631837 @default.
- W2405521796 cites W2031197851 @default.
- W2405521796 cites W2035694723 @default.
- W2405521796 cites W2041237128 @default.
- W2405521796 cites W2046642294 @default.
- W2405521796 cites W2050034917 @default.
- W2405521796 cites W2050819498 @default.
- W2405521796 cites W2051075676 @default.
- W2405521796 cites W2051149654 @default.
- W2405521796 cites W2051431017 @default.
- W2405521796 cites W2051846676 @default.
- W2405521796 cites W2056109880 @default.
- W2405521796 cites W2065589217 @default.
- W2405521796 cites W2066001495 @default.
- W2405521796 cites W2066472053 @default.
- W2405521796 cites W2068170186 @default.
- W2405521796 cites W2068389518 @default.
- W2405521796 cites W2068998607 @default.
- W2405521796 cites W2069384383 @default.
- W2405521796 cites W2073459098 @default.
- W2405521796 cites W2076110748 @default.
- W2405521796 cites W2078696801 @default.
- W2405521796 cites W2084023771 @default.
- W2405521796 cites W2086155248 @default.
- W2405521796 cites W2088993691 @default.
- W2405521796 cites W2089220405 @default.
- W2405521796 cites W2090839806 @default.
- W2405521796 cites W2091270126 @default.
- W2405521796 cites W2094599182 @default.
- W2405521796 cites W2096799690 @default.
- W2405521796 cites W2101575023 @default.
- W2405521796 cites W2104196857 @default.
- W2405521796 cites W2109221460 @default.
- W2405521796 cites W2110506858 @default.
- W2405521796 cites W2111909972 @default.
- W2405521796 cites W2112233591 @default.
- W2405521796 cites W2114219043 @default.
- W2405521796 cites W2118944124 @default.
- W2405521796 cites W2119118503 @default.
- W2405521796 cites W2122635237 @default.
- W2405521796 cites W2123955922 @default.
- W2405521796 cites W2125300901 @default.
- W2405521796 cites W2125431158 @default.