Matches in SemOpenAlex for { <https://semopenalex.org/work/W2405831566> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2405831566 endingPage "4" @default.
- W2405831566 startingPage "501" @default.
- W2405831566 abstract "Although the vast majority of eccrine spiradenomas behave in a benign fashion, 23 cases of malignant transformation have been reported to date. We describe a unique example of malignant eccrine spiradenoma that arose in the right breast of a 68-year-old woman. The quiescent mass, which was present for approximately 50 years, experienced sudden enlargement with erythematous changes of the overlying skin and nipple discharge. Microscopically, the tumor showed the typical features of an eccrine spiradenoma with areas of adenocarcinoma, squamous cell carcinoma, and sarcoma. The sarcomatous component consisted of rhabdomyosarcoma and osteosarcoma. The immunoperoxidase staining revealed p53 protein expression only in the carcinomatous and sarcomatous components. This suggests that accumulation of p53 protein may be an important event in the malignant transformation of spiradenomas. Because of its location and biphasic nature, this malignant eccrine spiradenoma should be distinguished from metaplastic breast carcinoma. To our knowledge, this represents the first carcinosarcomatous transformation of eccrine spiradenoma in the breast. This case led us to conclude that breast tissue, which often undergoes apocrine metaplasia and gives rise to apocrine neoplasms, is also capable of originating benign and malignant tumors with eccrine sweat duct phenotype." @default.
- W2405831566 created "2016-06-24" @default.
- W2405831566 creator A5001411760 @default.
- W2405831566 creator A5007883912 @default.
- W2405831566 creator A5028596605 @default.
- W2405831566 creator A5032543853 @default.
- W2405831566 date "1996-05-01" @default.
- W2405831566 modified "2023-10-16" @default.
- W2405831566 title "Carcinosarcoma arising in eccrine spiradenoma of the breast. Report of a case and review of the literature." @default.
- W2405831566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8639057" @default.
- W2405831566 hasPublicationYear "1996" @default.
- W2405831566 type Work @default.
- W2405831566 sameAs 2405831566 @default.
- W2405831566 citedByCount "11" @default.
- W2405831566 countsByYear W24058315662012 @default.
- W2405831566 countsByYear W24058315662015 @default.
- W2405831566 countsByYear W24058315662017 @default.
- W2405831566 crossrefType "journal-article" @default.
- W2405831566 hasAuthorship W2405831566A5001411760 @default.
- W2405831566 hasAuthorship W2405831566A5007883912 @default.
- W2405831566 hasAuthorship W2405831566A5028596605 @default.
- W2405831566 hasAuthorship W2405831566A5032543853 @default.
- W2405831566 hasConcept C121608353 @default.
- W2405831566 hasConcept C126322002 @default.
- W2405831566 hasConcept C142724271 @default.
- W2405831566 hasConcept C150875184 @default.
- W2405831566 hasConcept C2776047466 @default.
- W2405831566 hasConcept C2777546739 @default.
- W2405831566 hasConcept C2778938455 @default.
- W2405831566 hasConcept C2779357193 @default.
- W2405831566 hasConcept C31033888 @default.
- W2405831566 hasConcept C530470458 @default.
- W2405831566 hasConcept C71924100 @default.
- W2405831566 hasConceptScore W2405831566C121608353 @default.
- W2405831566 hasConceptScore W2405831566C126322002 @default.
- W2405831566 hasConceptScore W2405831566C142724271 @default.
- W2405831566 hasConceptScore W2405831566C150875184 @default.
- W2405831566 hasConceptScore W2405831566C2776047466 @default.
- W2405831566 hasConceptScore W2405831566C2777546739 @default.
- W2405831566 hasConceptScore W2405831566C2778938455 @default.
- W2405831566 hasConceptScore W2405831566C2779357193 @default.
- W2405831566 hasConceptScore W2405831566C31033888 @default.
- W2405831566 hasConceptScore W2405831566C530470458 @default.
- W2405831566 hasConceptScore W2405831566C71924100 @default.
- W2405831566 hasIssue "5" @default.
- W2405831566 hasLocation W24058315661 @default.
- W2405831566 hasOpenAccess W2405831566 @default.
- W2405831566 hasPrimaryLocation W24058315661 @default.
- W2405831566 hasRelatedWork W183921608 @default.
- W2405831566 hasRelatedWork W2003790128 @default.
- W2405831566 hasRelatedWork W2059303218 @default.
- W2405831566 hasRelatedWork W2095965162 @default.
- W2405831566 hasRelatedWork W2133343642 @default.
- W2405831566 hasRelatedWork W2158159495 @default.
- W2405831566 hasRelatedWork W2318941074 @default.
- W2405831566 hasRelatedWork W2405831566 @default.
- W2405831566 hasRelatedWork W2416356519 @default.
- W2405831566 hasRelatedWork W3031971296 @default.
- W2405831566 hasVolume "120" @default.
- W2405831566 isParatext "false" @default.
- W2405831566 isRetracted "false" @default.
- W2405831566 magId "2405831566" @default.
- W2405831566 workType "article" @default.