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• W2405895593 abstract "Chagas disease is a serious illness caused by the protozoan parasite Trypanosoma cruzi. Nearly 30% of chronically infected people develop cardiac, digestive or mixed alterations, suggesting a broad range of host-parasite interactions that finally impact upon chronic disease outcome. The ability of T. cruzi to persist and cause pathology seems to depend on diverse factors like T. cruzi strains and the infective load, the route of infection, the release of immunomodulatory or virulence factors, the parasite capacity of avoid protective immune response, the strength and type of host defence mechanisms and the genetic background of the host. In this context, the host-parasite interaction is subject to a constant neuro-endocrine regulation, and as the infection proceeds can lead to a broad range of outcomes, from elimination of the pathogen to its continued persistence in the host with the consequent induction of pathology. In particular, neuro-endocrine balance, effector and regulatory T cells are key points where the host can take advantage to improve their defence mechanisms, or contrarily may be exploited by parasites to survive and persist. In this context, T. cruzi evasion strategies and host defence mechanisms can be envisioned as two sides from the same coin at the complex host-parasite relationship influencing parasite persistence and different outcomes observed in Chagas disease. Understanding on how T. cruzi evade innate and adaptive immune response and how parasite persistence might be favoured by immuno-neuro-endocrine regulation will provide important clues to better dissect mechanisms underlying the pathophysiology of Chagas disease." @default.
• W2405895593 created "2016-06-24" @default.
• W2405895593 creator A5024312874 @default.
• W2405895593 creator A5048848100 @default.
• W2405895593 creator A5062682761 @default.
• W2405895593 creator A5065159433 @default.
• W2405895593 date "2016-05-23" @default.
• W2405895593 modified "2023-10-14" @default.
• W2405895593 title "Evasion and Immuno-Endocrine Regulation in Parasite Infection: Two Sides of the Same Coin in Chagas Disease?" @default.
• W2405895593 cites W119695767 @default.
• W2405895593 cites W1489445152 @default.
• W2405895593 cites W1489889255 @default.
• W2405895593 cites W1491762297 @default.
• W2405895593 cites W1503504963 @default.
• W2405895593 cites W1510374934 @default.
• W2405895593 cites W1521292935 @default.
• W2405895593 cites W1546298479 @default.
• W2405895593 cites W1569612497 @default.
• W2405895593 cites W1574045438 @default.
• W2405895593 cites W1619437296 @default.
• W2405895593 cites W1679720452 @default.
• W2405895593 cites W1690540890 @default.
• W2405895593 cites W1745179720 @default.
• W2405895593 cites W1892410119 @default.
• W2405895593 cites W1902848540 @default.
• W2405895593 cites W1929210873 @default.
• W2405895593 cites W1931237845 @default.
• W2405895593 cites W1965633191 @default.
• W2405895593 cites W1968041774 @default.
• W2405895593 cites W1969866472 @default.
• W2405895593 cites W1970973247 @default.
• W2405895593 cites W1971229305 @default.
• W2405895593 cites W1973541498 @default.
• W2405895593 cites W1973924070 @default.
• W2405895593 cites W1975134979 @default.
• W2405895593 cites W1975518001 @default.
• W2405895593 cites W1975598294 @default.
• W2405895593 cites W1977645089 @default.
• W2405895593 cites W1977736130 @default.
• W2405895593 cites W1979245971 @default.
• W2405895593 cites W1981078229 @default.
• W2405895593 cites W1982245052 @default.
• W2405895593 cites W1984398545 @default.
• W2405895593 cites W1984734982 @default.
• W2405895593 cites W1986609722 @default.
• W2405895593 cites W1988819628 @default.
• W2405895593 cites W1993355276 @default.
• W2405895593 cites W1995839300 @default.
• W2405895593 cites W1997432386 @default.
• W2405895593 cites W1998086688 @default.
• W2405895593 cites W2002534697 @default.
• W2405895593 cites W2004600066 @default.
• W2405895593 cites W2008347561 @default.
• W2405895593 cites W2012195873 @default.
• W2405895593 cites W2012423405 @default.
• W2405895593 cites W2013824064 @default.
• W2405895593 cites W2016325370 @default.
• W2405895593 cites W2018313668 @default.
• W2405895593 cites W2021394845 @default.
• W2405895593 cites W2021863260 @default.
• W2405895593 cites W2022143262 @default.
• W2405895593 cites W2022712113 @default.
• W2405895593 cites W2023120585 @default.
• W2405895593 cites W2024102174 @default.
• W2405895593 cites W2028039565 @default.
• W2405895593 cites W2029572231 @default.
• W2405895593 cites W2033097140 @default.
• W2405895593 cites W2034325006 @default.
• W2405895593 cites W2036274873 @default.
• W2405895593 cites W2037298250 @default.
• W2405895593 cites W2037311731 @default.
• W2405895593 cites W2038641544 @default.
• W2405895593 cites W2047162021 @default.
• W2405895593 cites W2047306084 @default.
• W2405895593 cites W2053654209 @default.
• W2405895593 cites W2053714938 @default.
• W2405895593 cites W2054458565 @default.
• W2405895593 cites W2057815635 @default.
• W2405895593 cites W2059071126 @default.
• W2405895593 cites W2062173423 @default.
• W2405895593 cites W2064328571 @default.
• W2405895593 cites W2064953244 @default.
• W2405895593 cites W2066394646 @default.
• W2405895593 cites W2067223244 @default.
• W2405895593 cites W2067256176 @default.
• W2405895593 cites W2067753568 @default.
• W2405895593 cites W2070927523 @default.
• W2405895593 cites W2071190956 @default.
• W2405895593 cites W2072362340 @default.
• W2405895593 cites W2075655804 @default.
• W2405895593 cites W2075831413 @default.
• W2405895593 cites W2078382249 @default.
• W2405895593 cites W2087761193 @default.
• W2405895593 cites W2088330531 @default.
• W2405895593 cites W2088987598 @default.
• W2405895593 cites W2089866373 @default.
• W2405895593 cites W2095842810 @default.
• W2405895593 cites W2096638225 @default.
• W2405895593 cites W2098262910 @default.
• W2405895593 cites W2103554242 @default.

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