Matches in SemOpenAlex for { <https://semopenalex.org/work/W2405907555> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2405907555 abstract "AIM To investigate whether blood brain barrier (BBB) opens when the immune system is challenged. METHODS Lipopolysaccharide (LPS) from E.coli was injected intravenously to the rats as an immune stimulus, and/or a small dose (3 μg·kg -1 ) of adrenaline (AD) which could not open BBB itself was given intravenously to induce a mild transient hypertension. RESULTS Neither a large dose (250 μg·kg -1 ) of LPS nor a small dose of AD could open BBB when administered separately, while the same dose of AD opened BBB at the presence of LPS administered 3 h in advanced. CONCLUSION This result suggests that BBB open threshold is lowered and BBB is apt to open when the immune system is challenged. The present study offers some evidence for the hypothesis that immune informational molecules might enter the brain through transiently opened BBB." @default.
- W2405907555 created "2016-06-24" @default.
- W2405907555 creator A5076854121 @default.
- W2405907555 date "1999-01-01" @default.
- W2405907555 modified "2023-09-27" @default.
- W2405907555 title "Effect of intravenous injection of lipoplysaccharide and small dose of adrenaline on the opening of blood brain barrier" @default.
- W2405907555 hasPublicationYear "1999" @default.
- W2405907555 type Work @default.
- W2405907555 sameAs 2405907555 @default.
- W2405907555 citedByCount "0" @default.
- W2405907555 crossrefType "journal-article" @default.
- W2405907555 hasAuthorship W2405907555A5076854121 @default.
- W2405907555 hasConcept C126322002 @default.
- W2405907555 hasConcept C15744967 @default.
- W2405907555 hasConcept C203014093 @default.
- W2405907555 hasConcept C2778402981 @default.
- W2405907555 hasConcept C2778754761 @default.
- W2405907555 hasConcept C2779918689 @default.
- W2405907555 hasConcept C42219234 @default.
- W2405907555 hasConcept C529278444 @default.
- W2405907555 hasConcept C542102704 @default.
- W2405907555 hasConcept C71924100 @default.
- W2405907555 hasConcept C8891405 @default.
- W2405907555 hasConcept C98274493 @default.
- W2405907555 hasConceptScore W2405907555C126322002 @default.
- W2405907555 hasConceptScore W2405907555C15744967 @default.
- W2405907555 hasConceptScore W2405907555C203014093 @default.
- W2405907555 hasConceptScore W2405907555C2778402981 @default.
- W2405907555 hasConceptScore W2405907555C2778754761 @default.
- W2405907555 hasConceptScore W2405907555C2779918689 @default.
- W2405907555 hasConceptScore W2405907555C42219234 @default.
- W2405907555 hasConceptScore W2405907555C529278444 @default.
- W2405907555 hasConceptScore W2405907555C542102704 @default.
- W2405907555 hasConceptScore W2405907555C71924100 @default.
- W2405907555 hasConceptScore W2405907555C8891405 @default.
- W2405907555 hasConceptScore W2405907555C98274493 @default.
- W2405907555 hasLocation W24059075551 @default.
- W2405907555 hasOpenAccess W2405907555 @default.
- W2405907555 hasPrimaryLocation W24059075551 @default.
- W2405907555 hasRelatedWork W1729555903 @default.
- W2405907555 hasRelatedWork W181870677 @default.
- W2405907555 hasRelatedWork W1984466148 @default.
- W2405907555 hasRelatedWork W1987879935 @default.
- W2405907555 hasRelatedWork W2020203590 @default.
- W2405907555 hasRelatedWork W2027176817 @default.
- W2405907555 hasRelatedWork W2054140758 @default.
- W2405907555 hasRelatedWork W2078142633 @default.
- W2405907555 hasRelatedWork W2087240145 @default.
- W2405907555 hasRelatedWork W2105943668 @default.
- W2405907555 hasRelatedWork W2109722181 @default.
- W2405907555 hasRelatedWork W2169144851 @default.
- W2405907555 hasRelatedWork W2279654308 @default.
- W2405907555 hasRelatedWork W2407185414 @default.
- W2405907555 hasRelatedWork W2407609339 @default.
- W2405907555 hasRelatedWork W2409056693 @default.
- W2405907555 hasRelatedWork W2569001682 @default.
- W2405907555 hasRelatedWork W2743705856 @default.
- W2405907555 hasRelatedWork W2939176992 @default.
- W2405907555 hasRelatedWork W2943589147 @default.
- W2405907555 isParatext "false" @default.
- W2405907555 isRetracted "false" @default.
- W2405907555 magId "2405907555" @default.
- W2405907555 workType "article" @default.