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- W2405961671 abstract "Purpose: When choosing dressing method to treat skin defect by second degree or higher burn, we have to consider method of rapid epithelization and minimization of pain during the treatment. In this study, we used biologic dressing with cultured allogenic keratinocytes for skin defect due to burn. We followed up the degree of epithelization, the degree of pain, and patient satisfaction. Methods: From June 2003 to June 2006, among the patients with skin defect due to burn, 31 cases with second degree burn(moderate to severe) were selected and biological dressing with cultured allogenic keratinocytes were done. 21 cases did not use cultured allogenic keratinocytes. Most of the patients had second degree burn. We applied cultured allogenic keratinocyte by Kaloderm. For wounds that were not deep enough to effect the dermis, escharectomy was done before applying Kaloderm. After the operation, moist wound site was maintained by dressing with saline gauze for 5-7 days. We compared the condition of the wound site before and after applying Keloderm by grading epithelization by standardized percentage scoring scale(1-5), and degree of pain and patient satisfaction by visual analogue scale(0-10). Received March 31, 2008 Revised April 23, 2008 Accepted May 22, 2008 Address Correspondence: Jeong Su Shim, M.D., Department of Plastic and Reconstructive Surgery, College of Medicine, Catholic University of Daegu, 3056-6 Daemyung 4-dong Nam-gu, Daegu 705-718, Korea. Tel: 053)650-4578/Fax: 053)650-4584/E-mail: 21csue@hanmail.net Results: When cultured allogenic keratinocytes were applied for the same period of time, the mean score of epithelization were 3.29±0.529(mean±S.D.). Without the application, the mean score of epithelization were 2.86±0.655(mean±S.D.). The degree of pain was 7.71 ±1.419(mean±S.D.) and 2.35±0.950(mean±S.D.) before and after the application, respectively. The patients' satisfaction score was 6.45±0.850(mean± S.D.) and 8.45±0.961(mean±S.D.) before and after the application, respectively. Conclusion: Applying biological dressing with cultured allogenic keratinocyte to skin defect due to second degree burn showed satisfactory results in the degree of the epithelization, degree of pain and patients' satisfaction." @default.
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- W2405961671 date "2008-07-01" @default.
- W2405961671 modified "2023-09-23" @default.
- W2405961671 title "The Usefulnesssof Cultured Allogenic Keratinocyte for Burn Treatment" @default.
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