FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2406050555> ?p ?o ?g. }

• W2406050555 endingPage "162" @default.
• W2406050555 startingPage "147" @default.
• W2406050555 abstract "Gamma-band oscillations and their synchronization have been implicated in the coordination of activity between distributed neuronal assemblies in the service of sensory registration of stimuli and perceptual binding of their features. Prior electroencephalographic (EEG) studies of chronic schizophrenia patients have documented deficits in the magnitude and/or phase synchrony of stimulus-evoked gamma oscillations, findings that have been linked to neurotransmission abnormalities involving GABA and NMDA-glutamate receptors. However, it remains unclear whether these abnormalities are present at the onset of the illness, or indeed, whether they are present during the prodromal period preceding illness onset. Accordingly, we examined the magnitude and phase synchrony of the transient gamma-band response (GBR) elicited by an auditory stimulus in young patients with schizophrenia and in patients at clinical high risk for psychosis based on their manifestation of putatively prodromal symptoms.EEG was recorded during an auditory oddball target detection task in three groups: young schizophrenia patients early in their illness (YSZ; n = 19), patients at clinical high risk for psychosis (CHR; n = 55), and healthy controls (HC; n = 42). Single-trial EEG epochs and the average event-related potential time-locked to standard tones from the oddball task were subjected to time-frequency decomposition using Morlet wavelet transformations. The GBR between 50 and 100 ms following the tone onset was quantified in terms of evoked power, total power, and the phase-locking factor (PLF) reflecting cross-trial phase synchrony.GBR evoked power was significantly reduced in YSZ (p < 0.01) and CHR (p < 0.05) patients, relative to HC. Similarly, GBR PLF was significantly reduced in YSZ (p < 0.01) and showed a marginal reduction in CHR patients (p = 0.057), relative to HC. GBR total power was not reduced in CHR patients (p = 0.68) and showed only a trend level reduction in YSZ (p = 0.072). Within the CHR group. there were no significant GBR differences between the patients who converted to a psychotic disorder and those who did not convert to psychosis during a 12-month follow-up period.Reductions in the transient auditory GBR, as reflected by evoked power and phase synchrony, are evident in the early stages of schizophrenia and appear to precede psychosis onset. However, the absence of total power GBR abnormalities in CHR patients, with only a trend toward reduction in YSZ patients, suggests that the magnitude of the GBR is intact early in the course" @default.
• W2406050555 created "2016-06-24" @default.
• W2406050555 creator A5001798382 @default.
• W2406050555 creator A5020339164 @default.
• W2406050555 creator A5023116447 @default.
• W2406050555 creator A5047022638 @default.
• W2406050555 creator A5049296730 @default.
• W2406050555 creator A5053921657 @default.
• W2406050555 creator A5073531380 @default.
• W2406050555 date "2013-01-01" @default.
• W2406050555 modified "2023-10-16" @default.
• W2406050555 title "Early auditory gamma-band responses in patients at clinical high risk for schizophrenia" @default.
• W2406050555 cites W1973541245 @default.
• W2406050555 cites W1974123318 @default.
• W2406050555 cites W1983427160 @default.
• W2406050555 cites W1985328167 @default.
• W2406050555 cites W1985934303 @default.
• W2406050555 cites W1993380180 @default.
• W2406050555 cites W1997941792 @default.
• W2406050555 cites W2001429720 @default.
• W2406050555 cites W2003730487 @default.
• W2406050555 cites W2004699872 @default.
• W2406050555 cites W2005125144 @default.
• W2406050555 cites W2005839666 @default.
• W2406050555 cites W2012420986 @default.
• W2406050555 cites W2014357358 @default.
• W2406050555 cites W2015522794 @default.
• W2406050555 cites W2020507730 @default.
• W2406050555 cites W2022044536 @default.
• W2406050555 cites W2023122935 @default.
• W2406050555 cites W2023866997 @default.
• W2406050555 cites W2028697641 @default.
• W2406050555 cites W2028824762 @default.
• W2406050555 cites W2031142748 @default.
• W2406050555 cites W2039081480 @default.
• W2406050555 cites W2042415497 @default.
• W2406050555 cites W2045394963 @default.
• W2406050555 cites W2047347093 @default.
• W2406050555 cites W2054728313 @default.
• W2406050555 cites W2056870850 @default.
• W2406050555 cites W2066213630 @default.
• W2406050555 cites W2067393309 @default.
• W2406050555 cites W2068741295 @default.
• W2406050555 cites W2070523825 @default.
• W2406050555 cites W2073239561 @default.
• W2406050555 cites W2075241015 @default.
• W2406050555 cites W2076257356 @default.
• W2406050555 cites W2076361433 @default.
• W2406050555 cites W2081063176 @default.
• W2406050555 cites W2082733297 @default.
• W2406050555 cites W2082857490 @default.
• W2406050555 cites W2083537734 @default.
• W2406050555 cites W2087622664 @default.
• W2406050555 cites W2089692573 @default.
• W2406050555 cites W2089912569 @default.
• W2406050555 cites W2091541963 @default.
• W2406050555 cites W2091959742 @default.
• W2406050555 cites W2094383054 @default.
• W2406050555 cites W2095060637 @default.
• W2406050555 cites W2095265457 @default.
• W2406050555 cites W2096450505 @default.
• W2406050555 cites W2099427806 @default.
• W2406050555 cites W2102546182 @default.
• W2406050555 cites W2103926490 @default.
• W2406050555 cites W2106257034 @default.
• W2406050555 cites W2114512489 @default.
• W2406050555 cites W2115825472 @default.
• W2406050555 cites W2124019844 @default.
• W2406050555 cites W2125386334 @default.
• W2406050555 cites W2128495200 @default.
• W2406050555 cites W2135023185 @default.
• W2406050555 cites W2135861595 @default.
• W2406050555 cites W2138925878 @default.
• W2406050555 cites W2139196515 @default.
• W2406050555 cites W2140327288 @default.
• W2406050555 cites W2140824803 @default.
• W2406050555 cites W2141641254 @default.
• W2406050555 cites W2141890975 @default.
• W2406050555 cites W2143017628 @default.
• W2406050555 cites W2147190696 @default.
• W2406050555 cites W2147736098 @default.
• W2406050555 cites W2152401380 @default.
• W2406050555 cites W2155275431 @default.
• W2406050555 cites W2157331283 @default.
• W2406050555 cites W2159399714 @default.
• W2406050555 cites W2167456538 @default.
• W2406050555 cites W2170696995 @default.
• W2406050555 cites W2171907536 @default.
• W2406050555 cites W25444182 @default.
• W2406050555 cites W39535334 @default.
• W2406050555 cites W4238844806 @default.
• W2406050555 cites W4255830721 @default.
• W2406050555 doi "https://doi.org/10.1016/b978-0-7020-5307-8.00010-7" @default.
• W2406050555 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4120874" @default.
• W2406050555 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24053038" @default.
• W2406050555 hasPublicationYear "2013" @default.
• W2406050555 type Work @default.
• W2406050555 sameAs 2406050555 @default.

• next