Matches in SemOpenAlex for { <https://semopenalex.org/work/W2406133348> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2406133348 endingPage "85" @default.
- W2406133348 startingPage "379" @default.
- W2406133348 abstract "Frequently, the effects of a drug are studied in the presence of another drug which decreases the baseline for the action of the first drug. This may pose problems in terms of the evaluation of the action of interaction of one or both of the interacting drugs. When the effect of the interacting drugs (or conditions) are independent, the resulting effects of a drug A at a decreased baseline can be expected to conform to the equation given in this paper. If there is true, interactive antagonism, the resulting effect will not conform to this equation. The consequence of an independent interaction, which is in agreement with the equation given, is that the net effects of A are not affected by B, although B decreases the baseline for the action of A. Hence, the net effects of A are actually independent of (changes in) the baseline, and can best be described by the term pseudo-antagonism or baseline-antagonism. Experimental evidence is provided for such independent antagonistic interventions. These findings also give an explanation for phenomena related to the law of initial value (1)." @default.
- W2406133348 created "2016-06-24" @default.
- W2406133348 creator A5031557614 @default.
- W2406133348 creator A5058350017 @default.
- W2406133348 creator A5083574960 @default.
- W2406133348 date "1982-08-01" @default.
- W2406133348 modified "2023-09-26" @default.
- W2406133348 title "Evaluation and interpretation of dose response experiments with decreased baseline." @default.
- W2406133348 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6216378" @default.
- W2406133348 hasPublicationYear "1982" @default.
- W2406133348 type Work @default.
- W2406133348 sameAs 2406133348 @default.
- W2406133348 citedByCount "2" @default.
- W2406133348 crossrefType "journal-article" @default.
- W2406133348 hasAuthorship W2406133348A5031557614 @default.
- W2406133348 hasAuthorship W2406133348A5058350017 @default.
- W2406133348 hasAuthorship W2406133348A5083574960 @default.
- W2406133348 hasConcept C121332964 @default.
- W2406133348 hasConcept C126322002 @default.
- W2406133348 hasConcept C12725497 @default.
- W2406133348 hasConcept C170493617 @default.
- W2406133348 hasConcept C2777383412 @default.
- W2406133348 hasConcept C2780035454 @default.
- W2406133348 hasConcept C2780791683 @default.
- W2406133348 hasConcept C33923547 @default.
- W2406133348 hasConcept C505870484 @default.
- W2406133348 hasConcept C62520636 @default.
- W2406133348 hasConcept C71924100 @default.
- W2406133348 hasConcept C86380466 @default.
- W2406133348 hasConcept C86803240 @default.
- W2406133348 hasConcept C97320921 @default.
- W2406133348 hasConcept C98274493 @default.
- W2406133348 hasConceptScore W2406133348C121332964 @default.
- W2406133348 hasConceptScore W2406133348C126322002 @default.
- W2406133348 hasConceptScore W2406133348C12725497 @default.
- W2406133348 hasConceptScore W2406133348C170493617 @default.
- W2406133348 hasConceptScore W2406133348C2777383412 @default.
- W2406133348 hasConceptScore W2406133348C2780035454 @default.
- W2406133348 hasConceptScore W2406133348C2780791683 @default.
- W2406133348 hasConceptScore W2406133348C33923547 @default.
- W2406133348 hasConceptScore W2406133348C505870484 @default.
- W2406133348 hasConceptScore W2406133348C62520636 @default.
- W2406133348 hasConceptScore W2406133348C71924100 @default.
- W2406133348 hasConceptScore W2406133348C86380466 @default.
- W2406133348 hasConceptScore W2406133348C86803240 @default.
- W2406133348 hasConceptScore W2406133348C97320921 @default.
- W2406133348 hasConceptScore W2406133348C98274493 @default.
- W2406133348 hasIssue "6" @default.
- W2406133348 hasLocation W24061333481 @default.
- W2406133348 hasOpenAccess W2406133348 @default.
- W2406133348 hasPrimaryLocation W24061333481 @default.
- W2406133348 hasRelatedWork W1517395138 @default.
- W2406133348 hasRelatedWork W1590817999 @default.
- W2406133348 hasRelatedWork W2070508276 @default.
- W2406133348 hasRelatedWork W2252681196 @default.
- W2406133348 hasRelatedWork W2322979026 @default.
- W2406133348 hasRelatedWork W2560517622 @default.
- W2406133348 hasRelatedWork W2794783788 @default.
- W2406133348 hasRelatedWork W2993898000 @default.
- W2406133348 hasRelatedWork W3015116507 @default.
- W2406133348 hasRelatedWork W4213271907 @default.
- W2406133348 hasVolume "4" @default.
- W2406133348 isParatext "false" @default.
- W2406133348 isRetracted "false" @default.
- W2406133348 magId "2406133348" @default.
- W2406133348 workType "article" @default.