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- W2406146997 abstract "In his letter, Alberti (1) does not challenge any of the central results in our paper (2), including the main proof that upward curvature in the logarithm of the unfolding rate of a protein as a function of an applied mechanical force implies that underlying energy landscape is multidimensional. However, he wonders if the switch in pathway in Src tyrosine kinase SH3 (Src homology 3) domain discovered in single-molecule pulling experiments (3, 4) applies to “living cells/physiological settings,” an issue that is not germane to our work (2), and, by … [↵][1]1To whom correspondence should be addressed. Email: dave.thirumalai{at}gmail.com. [1]: #xref-corresp-1-1" @default.
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- W2406146997 date "2016-05-25" @default.
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- W2406146997 title "Reply to Alberti: Are in vitro folding experiments relevant in vivo?" @default.
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- W2406146997 doi "https://doi.org/10.1073/pnas.1603395113" @default.
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