Matches in SemOpenAlex for { <https://semopenalex.org/work/W2406149527> ?p ?o ?g. }
- W2406149527 endingPage "e0154650" @default.
- W2406149527 startingPage "e0154650" @default.
- W2406149527 abstract "Cancer-related and primary lymphedema (LE) are associated with the production of adipose tissue (AT). Nothing is known, however, about the lipid-based molecules that comprise LE AT. We therefore analyzed lipid molecules in lipoaspirates and serum obtained from LE patients, and compared them to lipoaspirates from cosmetic surgery patients and healthy control cohort serum. LE patient serum analysis demonstrated that triglycerides, HDL- and LDL-cholesterol and lipid transport molecules remained within the normal range, with no alterations in individual fatty acids. The lipidomic analysis also identified 275 lipid-based molecules, including triacylglycerides, diacylglycerides, fatty acids and phospholipids in AT oil and fat. Although the majority of lipid molecules were present in a similar abundance in LE and non-LE samples, there were several small changes: increased C20:5-containing triacylglycerides, reduced C10:0 caprinic and C24:1 nervonic acids. LE AT oil also contained a signature of increased cyclopropane-type fatty acids and inflammatory mediators arachidonic acid and ceramides. Interestingly C20:5 and C22:6 omega-3-type lipids are increased in LE AT, correlating with LE years. Hence, LE AT has a normal lipid profile containing a signature of inflammation and omega-3-lipids. It remains unclear, however, whether these differences reflect a small-scale global metabolic disturbance or effects within localised inflammatory foci." @default.
- W2406149527 created "2016-06-24" @default.
- W2406149527 creator A5014264225 @default.
- W2406149527 creator A5021413336 @default.
- W2406149527 creator A5046673863 @default.
- W2406149527 creator A5049064733 @default.
- W2406149527 creator A5054994452 @default.
- W2406149527 creator A5060182601 @default.
- W2406149527 creator A5064403423 @default.
- W2406149527 creator A5075400365 @default.
- W2406149527 creator A5087913047 @default.
- W2406149527 creator A5089681901 @default.
- W2406149527 creator A5090164845 @default.
- W2406149527 date "2016-05-16" @default.
- W2406149527 modified "2023-09-27" @default.
- W2406149527 title "Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema" @default.
- W2406149527 cites W14104846 @default.
- W2406149527 cites W1788055438 @default.
- W2406149527 cites W1879454470 @default.
- W2406149527 cites W1888852352 @default.
- W2406149527 cites W1923747726 @default.
- W2406149527 cites W1926751963 @default.
- W2406149527 cites W1964249139 @default.
- W2406149527 cites W1968237864 @default.
- W2406149527 cites W1982578021 @default.
- W2406149527 cites W1990489133 @default.
- W2406149527 cites W1991298929 @default.
- W2406149527 cites W1993794497 @default.
- W2406149527 cites W1997944980 @default.
- W2406149527 cites W1999331763 @default.
- W2406149527 cites W2001878481 @default.
- W2406149527 cites W2012318009 @default.
- W2406149527 cites W2014081215 @default.
- W2406149527 cites W2017602185 @default.
- W2406149527 cites W2019543527 @default.
- W2406149527 cites W2021760270 @default.
- W2406149527 cites W2021882008 @default.
- W2406149527 cites W2022399479 @default.
- W2406149527 cites W2022514684 @default.
- W2406149527 cites W2028980771 @default.
- W2406149527 cites W2033883349 @default.
- W2406149527 cites W2034750464 @default.
- W2406149527 cites W2041665587 @default.
- W2406149527 cites W2044407438 @default.
- W2406149527 cites W2052469958 @default.
- W2406149527 cites W2055325448 @default.
- W2406149527 cites W2056188652 @default.
- W2406149527 cites W2056980068 @default.
- W2406149527 cites W2057819889 @default.
- W2406149527 cites W2059163200 @default.
- W2406149527 cites W2059262835 @default.
- W2406149527 cites W2060952111 @default.
- W2406149527 cites W2063199586 @default.
- W2406149527 cites W2063818538 @default.
- W2406149527 cites W2066868268 @default.
- W2406149527 cites W2067191792 @default.
- W2406149527 cites W2070200868 @default.
- W2406149527 cites W2071447017 @default.
- W2406149527 cites W2085390160 @default.
- W2406149527 cites W2088815468 @default.
- W2406149527 cites W2089303595 @default.
- W2406149527 cites W2094790462 @default.
- W2406149527 cites W2100236100 @default.
- W2406149527 cites W2101341463 @default.
- W2406149527 cites W2101904915 @default.
- W2406149527 cites W2104208472 @default.
- W2406149527 cites W2106663365 @default.
- W2406149527 cites W2109180944 @default.
- W2406149527 cites W2115954005 @default.
- W2406149527 cites W2116404316 @default.
- W2406149527 cites W2117978763 @default.
- W2406149527 cites W2121521800 @default.
- W2406149527 cites W2127633445 @default.
- W2406149527 cites W2128863723 @default.
- W2406149527 cites W2134774645 @default.
- W2406149527 cites W2135041305 @default.
- W2406149527 cites W2136930833 @default.
- W2406149527 cites W2144331646 @default.
- W2406149527 cites W2145634137 @default.
- W2406149527 cites W2146553975 @default.
- W2406149527 cites W2148994051 @default.
- W2406149527 cites W2149628585 @default.
- W2406149527 cites W2155124908 @default.
- W2406149527 cites W2160486251 @default.
- W2406149527 cites W2170767542 @default.
- W2406149527 cites W2212127474 @default.
- W2406149527 cites W2214341650 @default.
- W2406149527 cites W2217305406 @default.
- W2406149527 cites W2330854548 @default.
- W2406149527 cites W2395274642 @default.
- W2406149527 cites W2412224812 @default.
- W2406149527 cites W2415538389 @default.
- W2406149527 cites W2464297455 @default.
- W2406149527 cites W2468983552 @default.
- W2406149527 cites W4250219259 @default.
- W2406149527 cites W746924942 @default.
- W2406149527 cites W88917156 @default.
- W2406149527 cites W1606366511 @default.