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- W2406203201 endingPage "128" @default.
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- W2406203201 abstract "Protein combinatorial libraries have become a platform technology for exploring protein sequence space for novel molecules for use in research, synthetic biology, biotechnology, and medicine. To expedite the isolation of proteins with novel/desired functions using screens and selections, high-quality approaches that generate protein libraries rich in folded and soluble structures are desirable for this goal. The binary patterning approach is a protein library design method that incorporates elements of both rational design and combinatorial diversity to specify the arrangement of polar and nonpolar amino acid residues in the context of a desired, folded tertiary structure template. An overview of the considerations necessary to design and construct binary patterned libraries of de novo and natural proteins is presented." @default.
- W2406203201 created "2016-06-24" @default.
- W2406203201 creator A5013951672 @default.
- W2406203201 date "2014-01-01" @default.
- W2406203201 modified "2023-10-18" @default.
- W2406203201 title "High-Quality Combinatorial Protein Libraries Using the Binary Patterning Approach" @default.
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- W2406203201 doi "https://doi.org/10.1007/978-1-4939-1486-9_6" @default.
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