Matches in SemOpenAlex for { <https://semopenalex.org/work/W2406352400> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2406352400 endingPage "207" @default.
- W2406352400 startingPage "189" @default.
- W2406352400 abstract "The inhibitory effects of selected drugs on the Arthus reaction, a model of immune-complex-induced tissue injury, were studied. The reverse passive Arthus reaction (RPAR) was elicited in the dorsal skin of rats, using bovine serum albumin and the gamma-globulin fraction of rabbit anti-BSA. The optimal amounts of antigen and antibody required to elicit the reaction, as well as the reaction kinetics, were examined. Chlorpheniramine, cyproheptadine, d-penicillamine, chloroquine, indomethacin, phenylbutazone, naproxen, and mefenamic acid were found to be inactive despite high doses; aspirin and ibuprofen were only weakly active. Hydrocortisone and colchicine were strong inhibitors of the RPAR: the calculated ED50 values were 13 mg/kg p.o. and 0.3 mg/kg i.v., respectively. The RPAR exhibits a different sensitivity to drug inhibition than conventional models of inflammation (e.g., carrageenin paw edema) end may be useful to detect new types of anti-inflammatory agents." @default.
- W2406352400 created "2016-06-24" @default.
- W2406352400 creator A5039270448 @default.
- W2406352400 creator A5046589108 @default.
- W2406352400 creator A5050524378 @default.
- W2406352400 creator A5083078698 @default.
- W2406352400 date "1982-02-01" @default.
- W2406352400 modified "2023-09-23" @default.
- W2406352400 title "The effects of anti-inflammatory and other agents on the rat dermal arthus reaction." @default.
- W2406352400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6122238" @default.
- W2406352400 hasPublicationYear "1982" @default.
- W2406352400 type Work @default.
- W2406352400 sameAs 2406352400 @default.
- W2406352400 citedByCount "7" @default.
- W2406352400 countsByYear W24063524002013 @default.
- W2406352400 crossrefType "journal-article" @default.
- W2406352400 hasAuthorship W2406352400A5039270448 @default.
- W2406352400 hasAuthorship W2406352400A5046589108 @default.
- W2406352400 hasAuthorship W2406352400A5050524378 @default.
- W2406352400 hasAuthorship W2406352400A5083078698 @default.
- W2406352400 hasConcept C142724271 @default.
- W2406352400 hasConcept C170493617 @default.
- W2406352400 hasConcept C178790620 @default.
- W2406352400 hasConcept C185592680 @default.
- W2406352400 hasConcept C203014093 @default.
- W2406352400 hasConcept C204787440 @default.
- W2406352400 hasConcept C2775844104 @default.
- W2406352400 hasConcept C2775864247 @default.
- W2406352400 hasConcept C2776914184 @default.
- W2406352400 hasConcept C2776946954 @default.
- W2406352400 hasConcept C2777628954 @default.
- W2406352400 hasConcept C2778115740 @default.
- W2406352400 hasConcept C2778139025 @default.
- W2406352400 hasConcept C2778206117 @default.
- W2406352400 hasConcept C2778475344 @default.
- W2406352400 hasConcept C2779142470 @default.
- W2406352400 hasConcept C2779348387 @default.
- W2406352400 hasConcept C2779944601 @default.
- W2406352400 hasConcept C2781227287 @default.
- W2406352400 hasConcept C55493867 @default.
- W2406352400 hasConcept C71924100 @default.
- W2406352400 hasConcept C8891405 @default.
- W2406352400 hasConcept C98274493 @default.
- W2406352400 hasConceptScore W2406352400C142724271 @default.
- W2406352400 hasConceptScore W2406352400C170493617 @default.
- W2406352400 hasConceptScore W2406352400C178790620 @default.
- W2406352400 hasConceptScore W2406352400C185592680 @default.
- W2406352400 hasConceptScore W2406352400C203014093 @default.
- W2406352400 hasConceptScore W2406352400C204787440 @default.
- W2406352400 hasConceptScore W2406352400C2775844104 @default.
- W2406352400 hasConceptScore W2406352400C2775864247 @default.
- W2406352400 hasConceptScore W2406352400C2776914184 @default.
- W2406352400 hasConceptScore W2406352400C2776946954 @default.
- W2406352400 hasConceptScore W2406352400C2777628954 @default.
- W2406352400 hasConceptScore W2406352400C2778115740 @default.
- W2406352400 hasConceptScore W2406352400C2778139025 @default.
- W2406352400 hasConceptScore W2406352400C2778206117 @default.
- W2406352400 hasConceptScore W2406352400C2778475344 @default.
- W2406352400 hasConceptScore W2406352400C2779142470 @default.
- W2406352400 hasConceptScore W2406352400C2779348387 @default.
- W2406352400 hasConceptScore W2406352400C2779944601 @default.
- W2406352400 hasConceptScore W2406352400C2781227287 @default.
- W2406352400 hasConceptScore W2406352400C55493867 @default.
- W2406352400 hasConceptScore W2406352400C71924100 @default.
- W2406352400 hasConceptScore W2406352400C8891405 @default.
- W2406352400 hasConceptScore W2406352400C98274493 @default.
- W2406352400 hasIssue "2" @default.
- W2406352400 hasLocation W24063524001 @default.
- W2406352400 hasOpenAccess W2406352400 @default.
- W2406352400 hasPrimaryLocation W24063524001 @default.
- W2406352400 hasRelatedWork W1478225707 @default.
- W2406352400 hasRelatedWork W1527028879 @default.
- W2406352400 hasRelatedWork W1985093265 @default.
- W2406352400 hasRelatedWork W2016674637 @default.
- W2406352400 hasRelatedWork W2341074767 @default.
- W2406352400 hasRelatedWork W2395138316 @default.
- W2406352400 hasRelatedWork W2406352400 @default.
- W2406352400 hasRelatedWork W2438212343 @default.
- W2406352400 hasRelatedWork W2801652851 @default.
- W2406352400 hasRelatedWork W65452416 @default.
- W2406352400 hasVolume "35" @default.
- W2406352400 isParatext "false" @default.
- W2406352400 isRetracted "false" @default.
- W2406352400 magId "2406352400" @default.
- W2406352400 workType "article" @default.