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- W2406449063 abstract "Objective To study the clinical and imaging features,the diagnosis and management of orbital Langerhans cell histocytosis.Methods The symptoms,signs,imaging features,treatment and follow-up results of 11 cases of orbital Langerhans cell histocytosis were reviewed and analyzed,including 7 cases of eosinophilic granuloma and 4 cases of Hand-Schueller-Christian disease.Results Eosinophilic granuloma occurred primarily in children and teenagers and appeared as orbital lesions only.Hand-Schueller- Christian disease occurred in children under 5 years old,with multiple lesions of histocytosis.Typical cases showed the Hand-Schueller-Christian triad:exophthalmos,diabetes insipidus and bony skull defects. Patients usually complained of exophthalmos and orbital masses.B scan and color Doppler showed soft tissue masses in the orbit.CT showed soft tissue masses and bony skull defects.MRI showed orbital tumor and intracranial involvement.Conclusions Characteristic imaging features are helpful for the diagnosis of orbital Langerhans cell histocytosis.The treatment includes surgical excision,local radiotherapy or chemotherapy.The prognosis is related to the types of lesion,eosinophilic granuloma shows the best prognosis and infantile Hand-Schueller-Christian disease shows the worst prognosis.(Chin J Ophthalmol, 2006,42:892-895)" @default.
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- W2406449063 date "2006-10-01" @default.
- W2406449063 modified "2023-09-25" @default.
- W2406449063 title "Clinical analysis of 11 cases of orbital Langerhans cell histiocytosis" @default.
- W2406449063 doi "https://doi.org/10.3760/j:issn:0412-4081.2006.10.007" @default.
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