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• W2406507226 abstract "No AccessJournal of Urology1 Feb 1991The Incidence and Prognostic Significance of Humoral Hypercalcemia in Renal Cell Carcinoma Huei-Jyh Fahn, Ying-Huei Lee, Ming-Tsun Chen, Jong-Khing Huang, Kuang-Kuo Chen, and Luke S. Chang Huei-Jyh FahnHuei-Jyh Fahn More articles by this author , Ying-Huei LeeYing-Huei Lee More articles by this author , Ming-Tsun ChenMing-Tsun Chen More articles by this author , Jong-Khing HuangJong-Khing Huang More articles by this author , Kuang-Kuo ChenKuang-Kuo Chen More articles by this author , and Luke S. ChangLuke S. Chang More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)38305-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail This retrospective study was conducted to evaluate the incidence and prognostic significance of humoral hypercalcemia in 218 renal cell carcinoma patients during the last 20 years. Of 218 patients 20 (9.2%) were hypercalcemic, with serum calcium levels ranging from 10.7 to 16.0mg./dl. The respective incidence of humoral hypercalcemia was 3% in patients with stage I, 5.9% with stage II, 14.1% with stage III and 18.9% with stage IV disease without bone metastasis. The survival curves between the hypercalcemic and eucalcemic groups among stages I to III cancer patients showed no statistical significance (p>0.05). The survival curve deteriorated significantly in stage IV cancer patients with humoral hypercalcemia (p <0.005), with a median survival of 45.0 ± 39.7 days versus 286.4 ± 27.6 days in eucalcemic patients. No specific correlation was found between pathological cell type and humoral hypercalcemia. © 1991 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited BySaroha S, Uzzo R, Plimack E, Ruth K and Al-Saleem T (2018) Lymphopenia is an Independent Predictor of Inferior Outcome in Clear Cell Renal CarcinomaJournal of Urology, VOL. 189, NO. 2, (454-461), Online publication date: 1-Feb-2013.Walther M, Patel B, Choyke P, Lubensky I, Vocke C, Harris C, Venzon D, Burtis W and Linehan W (2018) Hypercalcemia in Patients With Metastatic Renal Cell Carcinoma: Effect of Nephrectomy and Metabolic EvaluationJournal of Urology, VOL. 158, NO. 3, (733-739), Online publication date: 1-Sep-1997.Weissglas M, Schamhart D, Lowik C, Papapoulos S, Vos P and Kurth K (2018) Investigative Urology: Hypercalcemia and Cosecretion of Interleukin-6 and Parathyroid Hormone Related Peptide by a Human Renal Cell Carcinoma Implanted Into Nude MiceJournal of Urology, VOL. 153, NO. 3, (854-857), Online publication date: 1-Mar-1995.Mani S, Todd M, Katz K and Poo W (2018) Prognostic Factors for Survival in Patients with Metastatic Renal Cancer Treated with Biological Response ModifiersJournal of Urology, VOL. 154, NO. 1, (35-40), Online publication date: 1-Jul-1995. Volume 145Issue 2February 1991Page: 248-250 Advertisement Copyright & Permissions© 1991 by The American Urological Association Education and Research, Inc.Keywordsrenal cellhypercalcemiacarcinomaMetricsAuthor Information Huei-Jyh Fahn More articles by this author Ying-Huei Lee More articles by this author Ming-Tsun Chen More articles by this author Jong-Khing Huang More articles by this author Kuang-Kuo Chen More articles by this author Luke S. Chang More articles by this author Expand All Advertisement Loading ..." @default.
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• W2406507226 title "The Incidence and Prognostic Significance of Humoral Hypercalcemia in Renal Cell Carcinoma" @default.
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