Matches in SemOpenAlex for { <https://semopenalex.org/work/W2406674525> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2406674525 endingPage "18" @default.
- W2406674525 startingPage "1608" @default.
- W2406674525 abstract "Thirteen patients with previously untreated advanced squamous cell carcinoma of the esophagus were treated with pre-radiation chemotherapy followed by radiation therapy. The chemotherapy consisted of two or three cycles of Cisplatin and 120 hour continuous infusion of 5-Fluorouracil. Three patients showed complete response (CR), three partial response (PR), three minor response (MR) and four non-response (NR). The overall response rate was 46%. The predominant side effects were nausea, vomiting and anorexia. Mild or moderate degree of anemia and leukocytopenia were also noticed. However, no serious toxicity was observed. Radiation therapy was administered to eleven of the thirteen patients, excluding one patient who refused it and one patient who died during chemotherapy. In two of the eleven cases, however, radiotherapy was discontinued because of MR, and surgery was performed. In one additional case, post-radiotherapy surgery was performed. One of these three cases received curative esophagectomy. After definitive treatment, CR was obtained in 54% (7 of 13), PR in 15% (2 of 13), MR in 15% and NR in 15%. The non-effective patients (PR + MR + NR) died within nine months after the initiation of treatment. Two of the CR patients later died, one due to local recurrence and another due to aortic-esophageal fistula with no residual cancer discovered at autopsy. The remaining CR patients are still alive and well, after 11.5 to 32 months. Although the follow-up period is yet short, the combination of radiation therapy with pre-radiotherapy chemotherapy appears to be an effective treatment." @default.
- W2406674525 created "2016-06-24" @default.
- W2406674525 creator A5061520884 @default.
- W2406674525 date "1990-08-20" @default.
- W2406674525 modified "2023-09-23" @default.
- W2406674525 title "[Combined radiotherapy and pre-radiation chemotherapy with cisplatin and 5-fluorouracil for advanced esophageal carcinoma. II. Clinical evaluation in cases with higher than T2 stage]." @default.
- W2406674525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2230444" @default.
- W2406674525 hasPublicationYear "1990" @default.
- W2406674525 type Work @default.
- W2406674525 sameAs 2406674525 @default.
- W2406674525 citedByCount "0" @default.
- W2406674525 crossrefType "journal-article" @default.
- W2406674525 hasAuthorship W2406674525A5061520884 @default.
- W2406674525 hasConcept C121608353 @default.
- W2406674525 hasConcept C126322002 @default.
- W2406674525 hasConcept C141071460 @default.
- W2406674525 hasConcept C146357865 @default.
- W2406674525 hasConcept C151730666 @default.
- W2406674525 hasConcept C2776694085 @default.
- W2406674525 hasConcept C2777297899 @default.
- W2406674525 hasConcept C2777546739 @default.
- W2406674525 hasConcept C2777819096 @default.
- W2406674525 hasConcept C2779742542 @default.
- W2406674525 hasConcept C2780580376 @default.
- W2406674525 hasConcept C2780852908 @default.
- W2406674525 hasConcept C2909463153 @default.
- W2406674525 hasConcept C509974204 @default.
- W2406674525 hasConcept C71924100 @default.
- W2406674525 hasConcept C86803240 @default.
- W2406674525 hasConceptScore W2406674525C121608353 @default.
- W2406674525 hasConceptScore W2406674525C126322002 @default.
- W2406674525 hasConceptScore W2406674525C141071460 @default.
- W2406674525 hasConceptScore W2406674525C146357865 @default.
- W2406674525 hasConceptScore W2406674525C151730666 @default.
- W2406674525 hasConceptScore W2406674525C2776694085 @default.
- W2406674525 hasConceptScore W2406674525C2777297899 @default.
- W2406674525 hasConceptScore W2406674525C2777546739 @default.
- W2406674525 hasConceptScore W2406674525C2777819096 @default.
- W2406674525 hasConceptScore W2406674525C2779742542 @default.
- W2406674525 hasConceptScore W2406674525C2780580376 @default.
- W2406674525 hasConceptScore W2406674525C2780852908 @default.
- W2406674525 hasConceptScore W2406674525C2909463153 @default.
- W2406674525 hasConceptScore W2406674525C509974204 @default.
- W2406674525 hasConceptScore W2406674525C71924100 @default.
- W2406674525 hasConceptScore W2406674525C86803240 @default.
- W2406674525 hasIssue "8" @default.
- W2406674525 hasLocation W24066745251 @default.
- W2406674525 hasOpenAccess W2406674525 @default.
- W2406674525 hasPrimaryLocation W24066745251 @default.
- W2406674525 hasRelatedWork W2166624265 @default.
- W2406674525 hasRelatedWork W2337262864 @default.
- W2406674525 hasRelatedWork W2350968793 @default.
- W2406674525 hasRelatedWork W2364743624 @default.
- W2406674525 hasRelatedWork W2374862613 @default.
- W2406674525 hasRelatedWork W2379168393 @default.
- W2406674525 hasRelatedWork W2405049888 @default.
- W2406674525 hasRelatedWork W2409999721 @default.
- W2406674525 hasRelatedWork W2412478299 @default.
- W2406674525 hasRelatedWork W2418581411 @default.
- W2406674525 hasVolume "25" @default.
- W2406674525 isParatext "false" @default.
- W2406674525 isRetracted "false" @default.
- W2406674525 magId "2406674525" @default.
- W2406674525 workType "article" @default.