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- W2406719097 abstract "Viralnervousnecrosis(VNN)of sevenbandgrouperEpinephelusseptemfasciatusat grow-outstages, which was characterizedby upsidedown swimmingor floatingbehavior, has been spreadingin Japan. The present study describespathogenicityof a nodavirusfound in diseased sevenbandgrouper. When youngsevenband grouperorjuvenileredspottedgrouperE. akaara were challengedby an intramuscularinjectionwiththe filtered homogenateof infectedorgans (brainand eye),abnormalswimmingbehavior andmortalitywereproduced,but someaffectedfishrecoveredfromthediseaseafterexhibitingthecharacterizedbehavior. Necrosisand vacuolationof the brainandretinal tissues,characteristicto VNN, wereproducedin thedeadandabnormally-swimming fish andtheviral antigensweredetectedin the degeneratednervecells by FATwithan anti-SJNNV(stripedjack nervousnecrosisvirus) serum. The infectionexperimentwith redspotted grouperalso indicated that rearing watertemperature(16-28°C) influenceddevelopmentof the disease: higher mortalityand earlierappearanceof thediseasesigns wereobservedat higherwater temperatures." @default.
- W2406719097 created "2016-06-24" @default.
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- W2406719097 date "1998-01-01" @default.
- W2406719097 modified "2023-09-25" @default.
- W2406719097 title "Pathogenicity of the Nodavirus Detectedfrom DiseasedSevenband Grouper Epinephelusseptemfasciatus" @default.
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