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• W2406763780 endingPage "457" @default.
• W2406763780 startingPage "451" @default.
• W2406763780 abstract "In developing countries, both marginal vitamin A status and intestinal helminths are common among children. Indonesian children (n = 309, 0.6-6.6 y), known to be infected with Ascaris lumbricoides, were randomized into six different treatment groups (A-F). The treatments included 210 mumol vitamin A supplement and a dose of 400 mg albendazole (5-propylthio-1H-benzimidazol-2-yl carbamic acid methyl ester) administered orally either at the same health visit (Groups B and F) or at different contact times during a 1-mo period (groups A, C, D and E). Vitamin A status was assessed both before and 3-4 wk after the treatments by the modified relative dose response (MRDR) test. Vitamin A supplementation was most important in improving the vitamin A status (P < 0.0001) of these children, whereas treatment for ascariasis alone (P = 0.370) and the statistical interaction between treatment for ascariasis and vitamin A (P = 0.752) were not. Serum retinol concentrations marginally improved (P = 0.051) in two of the groups that received vitamin A and albendazole but not in the third group that received vitamin A only. The MRDR test proved a better discriminator of the effects of these treatments on vitamin A status than changes in serum retinol concentrations." @default.
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• W2406763780 date "1996-02-01" @default.
• W2406763780 modified "2023-10-11" @default.
• W2406763780 title "Vitamin A Status of Indonesian Children Infected with Ascaris lumbricoides after Dosing with Vitamin A Supplements and Albendazole" @default.
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• W2406763780 doi "https://doi.org/10.1093/jn/126.2.451" @default.
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