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- W2406908435 abstract "Maprotiline is a tetracyclic antidepressant which appears to have accounted for a relatively large proportion of the seizures associated with antidepressant use. The literature proposes two mechanisms of seizure induction: interaction with other medications and concomitant medical conditions lowering the seizure threshold. Observations during a study of maprotiline blood levels suggest that elevated serum concentrations achieved with therapeutic doses may also be linked to the seizure-induction mechanism. Monitoring of maprotiline blood levels may help to identify patients at risk." @default.
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- W2406908435 date "1983-11-01" @default.
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- W2406908435 title "Seizures Associated with High Maprotiline Serum Concentrations" @default.
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- W2406908435 doi "https://doi.org/10.1177/070674378302800710" @default.
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