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- W2406932021 abstract "The method of obtaining the multi-unit gastrointestinal diffusion system (m-GDS), containing lithium acetate, consists in encapsulating the lithium acetate in a form of microballs and thereafter coating the resulting microballs with a porous membrane which controls the diffusion rats of the drug. For the coating, a water-insoluble polymer (cellulose acetate) and two types of polymer-modifying agents (cetyl alcohol and shellac) were used. In this paper in vitro studies of drug release from the unit in relation to the microballs' coating and mass, and exposed surface area of the capsules are presented. Most in vitro systems provide zero-order dry delivery by appropriate selection of manufacturing parameters." @default.
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- W2406932021 date "1990-02-01" @default.
- W2406932021 modified "2023-09-23" @default.
- W2406932021 title "Lithium acetate gastrointestinal diffusion system. Part 2: Lithium acetate multi-unit gastrointestinal diffusion system: preparation and release rate studies." @default.
- W2406932021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2339165" @default.
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