FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2407176562> ?p ?o ?g. }

• W2407176562 endingPage "419.e19" @default.
• W2407176562 startingPage "419.e13" @default.
• W2407176562 abstract "T cells play an important role in antitumor immunity, and molecules regulating T-cell activity could influence cancer susceptibility. The distinct role of coinhibitory receptors in immunosurveillance has been considered. B- and T-lymphocyte attenuator (BTLA) is one of these receptors, which negatively regulate immune responses. The aim of this study was to investigate the association between BTLA gene polymorphisms and susceptibility to renal cell carcinoma (RCC) in the Polish population. Altogether 282 patients with RCC and 480 healthy subjects were genotyped for the following polymorphisms: rs2705511, rs1982809, rs9288952, rs16859633, rs9288953, rs2705535, and rs1844089 using the TaqManSNP Genotyping Assays. Here, we found that the presence of rs1982809G allele (genotype GG+AG) is associated with increased risk of RCC (odds ratio = 1.38; 95% CI: 1.03–1.86; P = 0.03). In patients with clear-cell RCC (ccRCC) with high-grade (3 and 4) tumors, the frequency of rs1982809[GG] genotype was significantly higher as compared to those with low-grade (1 and 2) tumors and to the controls (0.14 vs. 0.06, P = 0.05 and 0.14 vs. 0.06, P = 0.04, respectively). Moreover, we have noticed the trend for overrepresentation of carriers of rs2705511C allele in patients with RCC as compared with the controls (0.51 vs. 0.44, P = 0.08) Haplotype rs2705511C/rs1982809G/rs9288952A/rs9288953T/rs2705535C/rs1844089G (CGATCG) increased the risk of RCC of 46% (odds ratio = 1.46; 95% CI: 1.08–1.96; Pcorrected = 0.05). Our results indicate that polymorphisms rs1982809 situated in 3′ UTR nearby region of BTLA gene might be considered as low-penetrating risk factor for RCC, but results have to be confirmed in further studies." @default.
• W2407176562 created "2016-06-24" @default.
• W2407176562 creator A5001035063 @default.
• W2407176562 creator A5010360970 @default.
• W2407176562 creator A5012938371 @default.
• W2407176562 creator A5019968775 @default.
• W2407176562 creator A5046580566 @default.
• W2407176562 creator A5058388777 @default.
• W2407176562 creator A5067622216 @default.
• W2407176562 creator A5068439280 @default.
• W2407176562 creator A5069543889 @default.
• W2407176562 date "2016-09-01" @default.
• W2407176562 modified "2023-10-13" @default.
• W2407176562 title "Association of 3′ nearby gene BTLA polymorphisms with the risk of renal cell carcinoma in the Polish population" @default.
• W2407176562 cites W1861152060 @default.
• W2407176562 cites W1969562496 @default.
• W2407176562 cites W1969880764 @default.
• W2407176562 cites W1983555686 @default.
• W2407176562 cites W1983622643 @default.
• W2407176562 cites W1990791112 @default.
• W2407176562 cites W1996814190 @default.
• W2407176562 cites W2013043293 @default.
• W2407176562 cites W2018412613 @default.
• W2407176562 cites W2030447006 @default.
• W2407176562 cites W2039545078 @default.
• W2407176562 cites W2044526719 @default.
• W2407176562 cites W2072951796 @default.
• W2407176562 cites W2084967753 @default.
• W2407176562 cites W2100989874 @default.
• W2407176562 cites W2109119735 @default.
• W2407176562 cites W2112015427 @default.
• W2407176562 cites W2118705059 @default.
• W2407176562 cites W2130048860 @default.
• W2407176562 cites W2147605136 @default.
• W2407176562 cites W2149385661 @default.
• W2407176562 cites W2151578735 @default.
• W2407176562 cites W2151601086 @default.
• W2407176562 cites W2158143713 @default.
• W2407176562 cites W2164018844 @default.
• W2407176562 cites W2167914935 @default.
• W2407176562 doi "https://doi.org/10.1016/j.urolonc.2016.04.010" @default.
• W2407176562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27234378" @default.
• W2407176562 hasPublicationYear "2016" @default.
• W2407176562 type Work @default.
• W2407176562 sameAs 2407176562 @default.
• W2407176562 citedByCount "17" @default.
• W2407176562 countsByYear W24071765622017 @default.
• W2407176562 countsByYear W24071765622019 @default.
• W2407176562 countsByYear W24071765622020 @default.
• W2407176562 countsByYear W24071765622021 @default.
• W2407176562 countsByYear W24071765622022 @default.
• W2407176562 countsByYear W24071765622023 @default.
• W2407176562 crossrefType "journal-article" @default.
• W2407176562 hasAuthorship W2407176562A5001035063 @default.
• W2407176562 hasAuthorship W2407176562A5010360970 @default.
• W2407176562 hasAuthorship W2407176562A5012938371 @default.
• W2407176562 hasAuthorship W2407176562A5019968775 @default.
• W2407176562 hasAuthorship W2407176562A5046580566 @default.
• W2407176562 hasAuthorship W2407176562A5058388777 @default.
• W2407176562 hasAuthorship W2407176562A5067622216 @default.
• W2407176562 hasAuthorship W2407176562A5068439280 @default.
• W2407176562 hasAuthorship W2407176562A5069543889 @default.
• W2407176562 hasBestOaLocation W24071765621 @default.
• W2407176562 hasConcept C104317684 @default.
• W2407176562 hasConcept C126322002 @default.
• W2407176562 hasConcept C135763542 @default.
• W2407176562 hasConcept C143998085 @default.
• W2407176562 hasConcept C156957248 @default.
• W2407176562 hasConcept C180754005 @default.
• W2407176562 hasConcept C197754878 @default.
• W2407176562 hasConcept C203014093 @default.
• W2407176562 hasConcept C2776090121 @default.
• W2407176562 hasConcept C2776885095 @default.
• W2407176562 hasConcept C2777472916 @default.
• W2407176562 hasConcept C2780237676 @default.
• W2407176562 hasConcept C2908647359 @default.
• W2407176562 hasConcept C54355233 @default.
• W2407176562 hasConcept C71924100 @default.
• W2407176562 hasConcept C86803240 @default.
• W2407176562 hasConcept C8891405 @default.
• W2407176562 hasConcept C90924648 @default.
• W2407176562 hasConcept C99454951 @default.
• W2407176562 hasConceptScore W2407176562C104317684 @default.
• W2407176562 hasConceptScore W2407176562C126322002 @default.
• W2407176562 hasConceptScore W2407176562C135763542 @default.
• W2407176562 hasConceptScore W2407176562C143998085 @default.
• W2407176562 hasConceptScore W2407176562C156957248 @default.
• W2407176562 hasConceptScore W2407176562C180754005 @default.
• W2407176562 hasConceptScore W2407176562C197754878 @default.
• W2407176562 hasConceptScore W2407176562C203014093 @default.
• W2407176562 hasConceptScore W2407176562C2776090121 @default.
• W2407176562 hasConceptScore W2407176562C2776885095 @default.
• W2407176562 hasConceptScore W2407176562C2777472916 @default.
• W2407176562 hasConceptScore W2407176562C2780237676 @default.
• W2407176562 hasConceptScore W2407176562C2908647359 @default.
• W2407176562 hasConceptScore W2407176562C54355233 @default.
• W2407176562 hasConceptScore W2407176562C71924100 @default.
• W2407176562 hasConceptScore W2407176562C86803240 @default.

• next