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- W2407198773 abstract "Skou ST, Roos EM, Laursen MB, Rathleff MS, Arendt-Nielsen L, Simonsen O, Rasmussen S. A randomized, controlled trial of total knee replacement. N Engl J Med. 2015 Oct 22;373(17):1597-606.### Question:In patients with knee osteoarthritis, is total knee replacement plus a 12-week nonsurgical treatment program more effective than nonsurgical treatment alone?### Design:Randomized (allocation concealed), blinded (outcome assessor and statistician), controlled trial with 12 months of follow-up.### Setting:Aalborg University Hospital, Aalborg, Denmark.### Patients:100 patients (mean age, 66 years; 62% women) with radiographically confirmed knee osteoarthritis who were eligible for total knee replacement. Patients with previous total knee replacement on the same knee, those requiring simultaneous total replacement of both knees, and those with severe knee pain in the previous week were excluded. All patients were included in the analysis.### Intervention:Patients were allocated to total knee replacement plus nonsurgical treatment (n = 50) or nonsurgical treatment alone (n = 50). The total knee replacement procedure followed standard methods using a total cemented prosthesis with patellar resurfacing (NexGen …" @default.
- W2407198773 created "2016-06-24" @default.
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- W2407198773 date "2016-05-18" @default.
- W2407198773 modified "2023-10-18" @default.
- W2407198773 title "Total Knee Replacement Plus Nonsurgical Treatment Was Better Than Nonsurgical Treatment Alone for Knee Osteoarthritis" @default.
- W2407198773 doi "https://doi.org/10.2106/jbjs.16.00208" @default.
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