FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2407209187> ?p ?o ?g. }

• W2407209187 abstract "Heart failure accounts for over 5 million cases in the U.S. A major onset of this is myocardial infarction, which causes the myocardium to loose cardiomyocytes and transform into a scar tissue. Given that the adult infarcted cardiac tissue has a limited ability to regenerate, alternative methods to restore the damaged area need to be developed. The goal of these approaches is to design an optimal scaffold that can retain and deliver cardiomyocytes at the site of damaged myocardium. This tissue engineering approach would allow cardiac reconstruction by replacing the lost cardiomyocytes, delivering the required biomolecules, as well as remodeling the extracellular matrix (ECM). In this study we investigate the effects of a variety of ECM substrates on the attachment, survival and ECM production by cardiomyocytes. We cultured rat cardiomyocytes for 21 days in eleven different substrates, including nanofiber coated plates and 3D hydrogels. Cell attachment and survival rates were analyzed both quantitatively and qualitatively. ELISA and fluorometric assays were performed to quantify the synthesis and release of ECM protein molecules by the cells under various culture conditions. The matrix protein deposition was also qualitatively analyzed using immunofluorescence staining and imaging. Finally, the production of MMPs-2, 9 and" @default.
• W2407209187 created "2016-06-24" @default.
• W2407209187 creator A5025167078 @default.
• W2407209187 date "2013-01-01" @default.
• W2407209187 modified "2023-09-27" @default.
• W2407209187 title "SCAFFOLD COMPOSITION AND ARCHITECTURE CRITICALLY REGULATE EXTRACELLULAR MATRIX SYNTHESIS BY CARDIOMYOCYTES" @default.
• W2407209187 cites W12375921 @default.
• W2407209187 cites W1483750164 @default.
• W2407209187 cites W1979862783 @default.
• W2407209187 cites W1985151220 @default.
• W2407209187 cites W1987787819 @default.
• W2407209187 cites W1988306902 @default.
• W2407209187 cites W1994589849 @default.
• W2407209187 cites W1995253842 @default.
• W2407209187 cites W1999203014 @default.
• W2407209187 cites W2005483844 @default.
• W2407209187 cites W2006948351 @default.
• W2407209187 cites W2013682430 @default.
• W2407209187 cites W2014413503 @default.
• W2407209187 cites W2018845952 @default.
• W2407209187 cites W2023396624 @default.
• W2407209187 cites W2026271436 @default.
• W2407209187 cites W2045312132 @default.
• W2407209187 cites W2047174916 @default.
• W2407209187 cites W2050856345 @default.
• W2407209187 cites W2054513293 @default.
• W2407209187 cites W2055389629 @default.
• W2407209187 cites W2059989280 @default.
• W2407209187 cites W2066561195 @default.
• W2407209187 cites W2068197397 @default.
• W2407209187 cites W2077367853 @default.
• W2407209187 cites W2094007386 @default.
• W2407209187 cites W2095798342 @default.
• W2407209187 cites W2095954988 @default.
• W2407209187 cites W2096237299 @default.
• W2407209187 cites W2098185891 @default.
• W2407209187 cites W2109774918 @default.
• W2407209187 cites W2114286636 @default.
• W2407209187 cites W2130744701 @default.
• W2407209187 cites W2137412139 @default.
• W2407209187 cites W2146275594 @default.
• W2407209187 cites W2158458245 @default.
• W2407209187 cites W2164663161 @default.
• W2407209187 cites W2172722284 @default.
• W2407209187 cites W2178127997 @default.
• W2407209187 cites W2232898687 @default.
• W2407209187 cites W2285300636 @default.
• W2407209187 cites W2320738167 @default.
• W2407209187 hasPublicationYear "2013" @default.
• W2407209187 type Work @default.
• W2407209187 sameAs 2407209187 @default.
• W2407209187 citedByCount "0" @default.
• W2407209187 crossrefType "journal-article" @default.
• W2407209187 hasAuthorship W2407209187A5025167078 @default.
• W2407209187 hasConcept C106487976 @default.
• W2407209187 hasConcept C108586683 @default.
• W2407209187 hasConcept C109523444 @default.
• W2407209187 hasConcept C12554922 @default.
• W2407209187 hasConcept C136229726 @default.
• W2407209187 hasConcept C171056886 @default.
• W2407209187 hasConcept C178790620 @default.
• W2407209187 hasConcept C185592680 @default.
• W2407209187 hasConcept C189165786 @default.
• W2407209187 hasConcept C43617362 @default.
• W2407209187 hasConcept C49892992 @default.
• W2407209187 hasConcept C55493867 @default.
• W2407209187 hasConcept C71924100 @default.
• W2407209187 hasConcept C86803240 @default.
• W2407209187 hasConcept C89429830 @default.
• W2407209187 hasConcept C95444343 @default.
• W2407209187 hasConceptScore W2407209187C106487976 @default.
• W2407209187 hasConceptScore W2407209187C108586683 @default.
• W2407209187 hasConceptScore W2407209187C109523444 @default.
• W2407209187 hasConceptScore W2407209187C12554922 @default.
• W2407209187 hasConceptScore W2407209187C136229726 @default.
• W2407209187 hasConceptScore W2407209187C171056886 @default.
• W2407209187 hasConceptScore W2407209187C178790620 @default.
• W2407209187 hasConceptScore W2407209187C185592680 @default.
• W2407209187 hasConceptScore W2407209187C189165786 @default.
• W2407209187 hasConceptScore W2407209187C43617362 @default.
• W2407209187 hasConceptScore W2407209187C49892992 @default.
• W2407209187 hasConceptScore W2407209187C55493867 @default.
• W2407209187 hasConceptScore W2407209187C71924100 @default.
• W2407209187 hasConceptScore W2407209187C86803240 @default.
• W2407209187 hasConceptScore W2407209187C89429830 @default.
• W2407209187 hasConceptScore W2407209187C95444343 @default.
• W2407209187 hasLocation W24072091871 @default.
• W2407209187 hasOpenAccess W2407209187 @default.
• W2407209187 hasPrimaryLocation W24072091871 @default.
• W2407209187 hasRelatedWork W1581866053 @default.
• W2407209187 hasRelatedWork W1979941994 @default.
• W2407209187 hasRelatedWork W2007279845 @default.
• W2407209187 hasRelatedWork W2012352580 @default.
• W2407209187 hasRelatedWork W2017041801 @default.
• W2407209187 hasRelatedWork W2036279456 @default.
• W2407209187 hasRelatedWork W2062121410 @default.
• W2407209187 hasRelatedWork W2101486157 @default.
• W2407209187 hasRelatedWork W2189816 @default.
• W2407209187 hasRelatedWork W2224089124 @default.
• W2407209187 hasRelatedWork W2317541397 @default.

• next